The inability to produce insulin is the cause of type I diabetes mellitus. Not being able to use insulin effectively causes Type II diabetes mellitus.
" A metabolic disease in which the body's inability to produce any or enough insulin causes elevated levels of glucose in the blood. "
Diabetes mellitus
The body's inability to produce insulin in diabetes leads to high levels of sugar in the blood, causing various health complications such as fatigue, frequent urination, increased thirst, and potential damage to organs like the kidneys, eyes, and nerves. Proper management of insulin levels is crucial for individuals with diabetes to maintain their health and prevent complications.
Lack of insulin is called diabetes, specifically type 1 diabetes which is characterized by the body's inability to produce insulin. Without insulin, the body cannot regulate blood sugar levels and utilize glucose for energy properly.
There basis of Type 1 diabetes has to do with the dysfunction of the beta cells of the pancreas and their inability to produce insulin. If there were a molecular basis it would be the absence of insulin which helps the body tissues utilize glucose.
Diabetes mellitus is caused by a dysfunction of the pancreas and its ability to produce insulin.
Growth hormone and insulin are both needed to uptake amino acids into cells. In GH deficiency cells produce more insulin receptors and become more sensitive to insulin. This causes increased uptake of glucose into cells.
As there are two types of diabetes mellitus- Type I, the body's inability to produce insulin, & Type II, the body's resistance to insulin produced. In the case of Type I, injectable insulin is the only known treatment. For Type II, oral medications can be used on their own, in combination with other oral meds, or in combination with injectable insulin.
When a cell has too little insulin, it can lead to high blood sugar levels because insulin helps cells absorb glucose from the bloodstream. This can result in symptoms such as excessive thirst, frequent urination, fatigue, and weight loss. Over time, consistently high blood sugar levels can damage organs and lead to complications like nerve damage, cardiovascular disease, and kidney problems.
The beta cells of the pancreas produce insulin and C-peptide, a byproduct of insulin. Source: Wikipedia
This would be type 2. Type 1 is a complete inability to make insulin. Type 1 used to be called juvenile diabetes.