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Much of the histamine in the body is produced by the granules in mast cells and basophils as part of a local immune response to the presence of invading bodies.

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Q: What cells release histamine How does the body respond to the release of histamine?
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What cells produce histamine?

histamine is produced by basophils and by mast cells found in nearby connective tissues. It is found in virtually all animal body cells.[


Where histamine is found in human body?

Histamine is found in the granules of mast cells where it is bound with an acidic protein and heparin(positively charged) while histamine itself is negatively charged.


What cells produce histamine in a type one hypersensitivity reaction?

Basophils Mast cells contain histamine. When they encounter a foreign body, they splay themselves and release histamines which then cause swelling and surround the foreign body so other parts of the immune system can rid the body of the foreign invader. Antihistamines offer much comfort.


What are anti-itch drugs?

Anti-itch drugs are usually antihistamine medicines taken by mouth or used topically, or in extreme needs can be taken by injection or intravenously. They are available over the counter and by prescription. They work to block the histamine receptors on cells by binding to them so histamine can not. When histamine is released by your body and attaches to cells, it causes cells to release chemicals that produce sneezing, itching, and other allergic responses. Common over the counter anti-itch drugs are cortisone topical medicines and Benadryl.


Where are stem cells in humans?

stem cells exist throughout the body and they respond to certain needs in the body by becoming specialized cells.


What are anti-histamines?

According to the Cleveland Clinic web site, "Antihistamines help relieve symptoms by blocking the action of histamine. Histamine is a naturally occurring substance that is released by the immune system after being exposed to an allergen. When you inhale an allergen, mast cells located in the nose and sinus membranes release histamine. Histamine then attaches to receptors on nearby blood vessels, causing them to enlarge (dilate). Histamine also binds to other receptors located in nasal tissues, causing redness, swelling, itching, and changes in the secretions. By blocking histamine receptors, antihistamines prevent symptoms" (Cleveland Clinic web site 11/10/2008). So in essence what is occurring is an antihistamine blocks the ability of the body's histamine to attach to the normal receptor to tell the body to have a runny nose, itchy eyes, swelling, etc. They do not inhibit the release of histamine, as this would affect a wide array of other vital body functions that rely on histamine to work properly (such as acid production in the stomach).


Does the human body produce its own anti-histamine and anti-inflammatories?

When your body is invaded by any virus, bacteria or even a splinter, it will respond with general inflammatory response chemicals These chemicals include histamine (mostly secreted by basophils, white blood cells found in connective tissue), kinins, prostaglandins (PGs), and complement.Vasodilation (dilation of blood vessels), stimulated by histamine and other chemicals, increases blood supply to the damaged area. This causes redness and an increase in local temperature. All of these responses are harmful to the pathogens causing the infection.


How does ranitidine work?

Ranitidine (Zantac) is an H2 blocker. Histamine is released by nerves to the stomach and bind to H2 receptors to signal the stomach to make acid. Ranitidine blocks this interactions and so decreases acid production. The drugs called "antihistamines" block the H1 histamine receptors so that histamine (the same chemical) released by immune cells can't interact with other immune cells to cause allergies.


Which granular leukocytes produce histamine and aid the body in controlling allergic reaction and other exaggerated immunologic responses?

Mast Cells


Can itching be caused by toxic release of some sort?

Yes. Usually it is caused by a histamine reaction from the body' immune system.


Where are mast cells found in the body?

Mast cells are found primarily in the skin and digestive system, including the liver and spleen, and produce histamine, a chemical most famous for its ability to cause itching.


Why is histamine dangerous?

When histamine is produced in the body, it can be over-produced because we are taking too much of one thing or another that our body cannot use.