All types of leukodystrophy are genetic (present at conception), progressive, and never spontaneously resolve. None of the leukodystrophies can be cured, and effective treatments are limited.
Canavan disease in Ashkenazi Jews, or globoid cell leukodystrophy (GLD) and metachromatic leukodystrophy (MLD) in Scandinavians.
They are all caused by either an abnormality in one of the protein components of myelin, or by a defective or missing enzyme that assists in the production or normal degradation of myelin
Einstin
The juvenile form of metachromatic leukodystrophy is characterized by gait disturbances, urinary incontinence, mental deterioration, and emotional difficulties
It was incorporated in 1982
Metachromatic leukodystrophy (MLD) is a rare degenerative neurological disease affecting the fatty covering that acts as an insulator around nerve fibers known as the myelin sheath.
I am not sure... Although, I suffer majorly from Hemi-Hyper Trophy. I am 13. It is very hard to deal with. Do you have Leukodystrophy oh Hemi-Hyper Trophy?
they occur in the brain
Liver and kidney falure.
The treatment team usually involves a neurologist , a pediatrician, an ophthalmologist, an orthopedist, a genetic counselor, a neurodevelopmental psychologist and a genetic and/or metabolic disease specialist
Adult metachromatic leukodystrophy is characterized by emotional disturbances and psychiatric symptoms. Disorders of movement and posture appear later. Dementia and decreased visual function also occur.
Metachromatic leukodystrophy (MLD), also called sulfatide lipidosis and arylsulfatase A (ARSA) deficiency, is inherited as an autosomal recessive trait, due to mutations in the arylsulfatase A (ARSA) gene