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atrophy
In any rheumatic disease muscle weakness can result atrophy, ie the joins in the area are painful to move leading to the muscle not being used, this in turn leads to the muscle weakening.
It is a progressive disorder that leads to increasing severity of motor dysfunction and subsequent deterioration of muscle strength, muscle tone, and motor coordination
autosomal dominant, comprising 5-10% of all Alzheimer's disease cases (a brain disease in which death of nerve cells leads to progressive dementia).
Amyotrophic lateral sclerosis (ALS), often referred to as "Lou Gehrig's Disease," is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body. The progressive degeneration of the motor neurons in ALS eventually leads to their death. When the motor neurons die, the ability of the brain to initiate and control muscle movement is lost. With voluntary muscle action progressively affected, patients in the later stages of the disease may become totally paralyzed. A-myo-trophic comes from the Greek language. "A" means no or negative. "Myo" refers to muscle, and "Trophic" means nourishment-"No muscle nourishment." When a muscle has no nourishment, it "atrophies" or wastes away. "Lateral" identifies the areas in a person's spinal cord where portions of the nerve cells that signal and control the muscles are located. As this area degenerates it leads to scarring or hardening ("sclerosis") in the region. As motor neurons degenerate, they can no longer send impulses to the muscle fibers that normally result in muscle movement. Early symptoms of ALS often include increasing muscle weakness, especially involving the arms and legs, speech, swallowing or breathing. When muscles no longer receive the messages from the motor neurons that they require to function, the muscles begin to atrophy (become smaller). Limbs begin to look "thinner" as muscle tissue atrophies.
ALS, often referred to as "Lou Gehrig's Disease," is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body. The progressive degeneration of the motor neurons in ALS eventually leads to their death.
debilitating neurodegenerative (progressive nervous system dysfunction) childhood disorder characterized by failure to thrive, enlarged liver, and progressive neurological deterioration, which generally leads to death by three years of age
Death usually occurs between 10 and 30 years after disease onset, typically as the result of pneumonia or a fall. Progressive weakness of respiratory and swallowing muscles leads to increased risk of respiratory infection
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A chronic autoimmune disease that affects the neuromuscular junction is myasthenia gravis. It leads to fluctuating muscle weakness and fatigue.
to much fat in adiet leads toheart disease because the fat surounds the heart and leads to heart attack.
Huntington's disease is a genetic condition that leads to early dementia. In other words, it leads to degeneration of the brain.