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A callus

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Q: What do you call an area of hardened skin on the underside orf your hand or foot?
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What is callus formation?

Hardened or thickened part of the skin, especially on the palm of the hand or sole of the foot, as from continual friction or pressure. Also called calosity.A callus (or callosity) is a toughened area of skin which has become relatively thick and hard in response to repeated friction, pressure, or other irritation. Rubbing that is too frequent or forceful will cause blisters rather than allow calluses to form.