There are two separate slang expressions you could be referencing:
What's up? - a longtime common inquiry asking someone what they are doing, or what is going on
Word up! - a more modern exclamation of agreement, approval, or enthusiasm
it mean shove it up your a hole
No, Up does not mean down. In fact, "down" is the antonym of "up"!
It mean was up bro? or was up dude?
It can mean to pay up. "I couldn't stump up the entrance fee."
what is snuggle mean
Any dog can grow up to be mean if not properly socillized.
mean;selfish;stuck-up
du has mean shut up
just look it up
Get up/Wake up/Stand up/Sit up
up mean on the surface and over mean in the space
If you mean: He just turned up at the show? It means that someone or something happened to be there.