They call your friend (female)...
you too my friend
------- likes school and your older female friend
"Tu mi amiga" means "you, my friend" in Spanish. It is a phrase used to address someone as a friend in a casual or familiar way.
It means, "Who is your best friend?" Amiga is a female friend.
você e sua amiga
You would say "Ella no es tu amiga." (or su amiga for the formal you, usted) If you mean 'She is not my friend' - "Ella no es mi amiga".
Friend (female), you speak Spanish.
What happened to your friend at low
With your friend (male) or your friend (female)
"Como se llama tu amiga" translates to "What is your friend's name?" in English. This is asking for the name of your friend.
What is your best friend like? (the best friend is female)
Translation: What is your best friend (female) called?