What does a high lymphocyte and a high MCH count mean?

Answer 1

Mean Corpuscular Hemoglobin (MCH) Normal Range: 26-34 pg (picograms/cell)

The mean corpuscular hemoglobin, or "mean cell hemoglobin" (MCH), is the average mass of hemoglobin per red blood cell in a sample of blood. It is reported as part of a standard complete blood count.

It is diminished inmicrocytic anemias and increasedin macrocytic anemias.

It is calculated by dividing the total mass of hemoglobin by the number of red blood cells in a volume of blood. MCH=Hgb/RBC reference: http://en.wikipedia.org/wiki/Mean_corpuscular_hemoglobin

---- Macrocytic Anemia

* Types of macrocytic anemias ** 1.1 Megaloblastic anemias (DNA replication disorders) ** 1.2 Red cell membrane disorders producing codocytes ** 1.3 Alcohol ** 1.4 Association with rapid red cell turnover and reticulocytosis * Especially common causes of macrocytic anemias are the so-called megaloblastic anemias, in which cells are larger because they cannot produce DNA quickly enough to divide at the right time as they grow, and thus grow too large before division. Causes for the DNA synthetic problem range from lack of certain vitamins needed to produce DNA (notablyfolate and B12), to poisons or inhibitors of DNA replication, such as some kinds of antiviral drugs and chemotherapeutic agents.

The remainder of the article can be seen on the following page

reference: http://en.wikipedia.org/wiki/Macrocytic_anemia

* Macrocytosis, sometimes without associated anemia, is often evident in persons with chronic alcoholism. Although the macrocytosis of Alcoholism may be secondary to poor nutrition with a resulting folate or vitamin B-12 deficiency, it is more often due to a direct toxicity of the alcohol on the marrow. The macrocytosis of alcoholism usually reverses only after months of abstinence from alcohol. The remainder of the article can be seen on the following page

reference: http://www.emedicine.com/med/topic1381.htm

Answer 2

MCHC is the average hemoglobin concentration in red blood cells. It is increased in a condition known as hereditary spherocytosis (red blood cells are spherical instead of the normal oval shape). It is also increased in hemolysis (break down of red blood cells). In addition, lipemia and cellular dehydration syndromes can lead to increase in MCHC.

Answer 3

mchc results aren't usually reported, it is mainly used as a guideline for analyser function, if MCHC is elevated it us a good indicator the analyser is in need of attention, i.e if it is averaging high. However if the result is true it is a good indicator of Cold agglutination taking place in the sample, if the mchc corrects after the sample has been warmed for >15minutes @37C this is clinically reportable, if the mchc does not correct and is only slightly elevated e.g 367 372 it can be a rare true case of hereditary spherocytosis. An elevated MCHC blood level on laboratory findings can also indicate a Vitamin B12 or folic acid deficiency.

A high MCH level in the blood can be due to a macrocytic anemia. This is typically an anemia caused by the inability of hemoglobin cells to divide properly before they get too big and are then inefficient at carrying the appropriate nutrients to the body. A Vitamin B12 deficiency, poisons, chemotherapy, alcoholism, and other chemicals that damage DNA which in turn doesn't make the blood components develop properly or split in time is also a factor in macrocytic anemia. In all these cases, the MCH will be elevated and an indicator of the physical disorder.

Answer 4

Lymphocyte Level: The average is 3,900-10,000. Lymphocytes are part of your immune system and are released if there is an infection that needs to be "fought" off. So therefore, if your count is higher than 10,000 you probably have some kind of infection that your body is fighting off. If it is excessively high (say the 100,000 range) it is possible that you may have leukemia (cancer of the white blood cells). I'm sure your doctor would have told you if it was extremely high - so most likely you just have an infection. MCH (Mean Corpuscular Hemoglobin) Level: The average is 32-36%. This measures the amount of hemoglobin in your blood (hemoglobin is what transports oxygen to your tissues). High levels are not a problem unless you have a certain genetic disorder which causes excessive amounts and too many red blood cells to be produced. You would already know if you had this problem. Most likely it is just the norm for you. Just to let you know, health care providers generally do not look at this number as any kind of indicator of anything - your hemoglobin and hematocrit are the numbers that are reviewed mostly when it comes to how your blood is functioning.

Answer 5

Mean Corpuscular Volume, it means the volume of your red blood cells is high, so big cells. Doens't have to say anything on its own.

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