What does a low platelet count mean?

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Platelets (thrombocytes) are a type of blood cells, which are derived in the bone marrow from large cells called megakaryocytes. They are critical for the clotting of blood and have a lifespan of about 10 days. The normal platelet count ranges from 150,000 - 400,000/ml and a reduction in platelets is referred to as thrombocytopenia. This may be mild (100,000 - 150,000/ml), moderate (50,000 - 100,000/mlƒw) or severe (less than 50,000/ml).

Platelets may be low due to:

a) Increased destruction (immunologic ¡V infections, drugs; gestational thrombocytopenia) or utilization (disseminated intra-vascular coagulation; abnormal vasculature as seen in hemolytic uremic syndrome & thrombotic thrombocytopenic purpura).

b) Decreased production (leukaemia, aplastic anaemia, megaloblastic anaemia, drugs, infections.

c) Sequestration in the spleen (cirrhosis of liver).

Idiopathic thrombocytopenic purpura (ITP) is the presence of isolated thrombocytopenia with a normal bone marrow and the absence of other causes to account for it.

Drugs can can cause platelet destruction by a variety of mechanisms. Platelet production in the marrow is inhibited by cytotoxic drugs, thiazide diuretics, interferon, and alcohol. Most often, drug-induced thrombocytopenia is mediated by immunological destruction of platelets via antibodies. Some common drugs associated with thrombocytopenia include quinidine, amiodarone, gold, captopril, sulfonamides, glibenclamide, carbamazepine, ibuprofen, cimetidine, tamoxifen, ranitidine, phenytoin, vancomycin, and piperacillin. The diagnosis of drug-induced thrombocytopenia is often empirical and it is often difficult to identify the drug that is causing severe thrombocytopenia in an acutely ill patient who is taking multiple drugs. A careful history and examination of medical records can reveal a temporal relationship between the administration of the drug and the development of thrombocytopenia, with no other explanations for the thrombocytopenia. Its recurrence following drug re-exposure confirms the diagnosis.

No treatment is required when the platelet counts are more than 50,000/ml. Treatment is indicated

a) when platelets are less 50,000/ml and there is significant mucous membrane bleeding;

b) in patients with hypertension, peptic ulcer disease or vigorous lifestyle who have a risk factor for bleeding

c) when platelet count <20,000-30,000/ml. Glucocorticoids and intra-venous gammaglobulins (I.V. Ig) are the mainstays of medical therapy. Their use and dose is dictated by the symptoms, patients clinical condition and the platelet count. Platelet transfusion is indicated for controlling severe hemorrhage. Platelet survival is increased if the platelets are transfused immediately after I.V. Ig infusion.

He can travel if the platelets are more than 50,000 and there are no signs of bleeding. Platelets (thrombocytes) are a type of blood cells, which are derived in the bone marrow from large cells called megakaryocytes. They are critical for the clotting of blood and have a lifespan of about 10 days. The normal platelet count ranges from 150,000 - 400,000/ml and a reduction in platelets is referred to as thrombocytopenia. This may be mild (100,000 - 150,000/ml), moderate (50,000 - 100,000/mlƒw) or severe (less than 50,000/ml).

Platelets may be low due to:

a) Increased destruction (immunologic ¡V infections, drugs; gestational thrombocytopenia) or utilization (disseminated intra-vascular coagulation; abnormal vasculature as seen in hemolytic uremic syndrome & thrombotic thrombocytopenic purpura).

b) Decreased production (leukaemia, aplastic anaemia, megaloblastic anaemia, drugs, infections.

c) Sequestration in the spleen (cirrhosis of liver).

Idiopathic thrombocytopenic purpura (ITP) is the presence of isolated thrombocytopenia with a normal bone marrow and the absence of other causes to account for it.

Drugs can can cause platelet destruction by a variety of mechanisms. Platelet production in the marrow is inhibited by cytotoxic drugs, thiazide diuretics, interferon, and alcohol. Most often, drug-induced thrombocytopenia is mediated by immunological destruction of platelets via antibodies. Some common drugs associated with thrombocytopenia include quinidine, amiodarone, gold, captopril, sulfonamides, glibenclamide, carbamazepine, ibuprofen, cimetidine, tamoxifen, ranitidine, phenytoin, vancomycin, and piperacillin. The diagnosis of drug-induced thrombocytopenia is often empirical and it is often difficult to identify the drug that is causing severe thrombocytopenia in an acutely ill patient who is taking multiple drugs. A careful history and examination of medical records can reveal a temporal relationship between the administration of the drug and the development of thrombocytopenia, with no other explanations for the thrombocytopenia. Its recurrence following drug re-exposure confirms the diagnosis.

No treatment is required when the platelet counts are more than 50,000/ml. Treatment is indicated

a) when platelets are less 50,000/ml and there is significant mucous membrane bleeding;

b) in patients with hypertension, peptic ulcer disease or vigorous lifestyle who have a risk factor for bleeding

c) when platelet count <20,000-30,000/ml. Glucocorticoids and intra-venous gammaglobulins (I.V. Ig) are the mainstays of medical therapy. Their use and dose is dictated by the symptoms, patients clinical condition and the platelet count. Platelet transfusion is indicated for controlling severe hemorrhage. Platelet survival is increased if the platelets are transfused immediately after I.V. Ig infusion.

He can travel if the platelets are more than 50,000 and there are no signs of bleeding.
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Why is the platelets count low in Acute Myeloid Leukemia?

Answer . \nThis is because the leukaemic cells in the bone marrow take over at the expense of the cells which produce platelets (megakaryocytes). They also affect the production of red blood cells (erythrocytes) leading to anaemia.\n. \nThe first signs of Acute Myeloid Leukaemia in the blood ar ( Full Answer )

What does a platelet count of ten mean?

Answer . A platlet count of 10 is actually 10,000 platlets. Platlets are the cells responsible for clotting. This is extremely low count and the person would be at risk for bleeding.

What does high platelet count mean?

my platelet count is 681, with neuts at 19.6, white blood cellcount over 26, and Vitamin B12 count at 917 - all way above theaverage range. What does this indicate?

What does low lymphocyte count mean?

Lymphocytes are white blood cells that protect the body frombacterial and viral attacks. A low lymphocyte count means a lowresistance to infection that could lead to various body organsbeing damaged.

How do you increase low platelet count?

It can be the common thing in cancer patients. It would be better for low platelet count patient to eat green vegetables and food which generates blood. If you infuse the platelet bag, then try to get the platelets of the same blood group. Like if your patient is having B+ blood, then donor should b ( Full Answer )

What does a low blood count of 6 mean?

"Blood count of 6" refers to a hemoglobin of 6. For females, the normal range of hemoglobing is 12-15 and this can vary slightly from one lab to another. For males, the normal range is 13.6-17.5 and again this can vary between the labs. A hemoglobin of 6 for either male or female is low. Hemoglobin ( Full Answer )

What is low platelet count?

I honestly don't know. Ask jesus. He knows everything. He even knows the hair on your penis or vagina. He knows it all.

What does it mean when your platelet count is low?

It means that you have thrombocytopenia, for which there are many causes. If the platelet count is below 50-75,000, then a serious medical investigation, starting with your physician, needs to begin. Slightly low values are usually nothing to worry about (125-150,000), and often self-correct with ti ( Full Answer )

What does it mean if you have low red and white blood cell counts and platelet count?

As with any medical prognosis, it depends on the overall condition and health of the person who has the "low" counts, and what "low" means. For example, being "low" by a few cells is probably meaningless, while having substantially "low" counts may indicate any of a number of conditions. So, without ( Full Answer )

What does a low liver count mean?

Low liver count is an indication that the liver is not functioningas it should be. This may be an indication of hepatitis or anyother form of liver damage.

2 weeks after an appendectomy have a high platelet count What could this mean?

Hello. It is not uncommon after surgery to have a rise in your platlets count as it is a repsonse by your bone marrow to restore any blood lost during surgery. Also, in regards to stress, the body can increase the production of blood products. However, having said that, (and not knowing your number ( Full Answer )

Is a 129 platelet count too low while doing chemotherapy?

Platelets are cells in your blood that help blood to clot. They are made in the bone marrow. Chemotherapy can cause your bone marrow to make less platelets and may make you prone to bruising or bleeding. A count of 129,000 (or referred to as 129 for short) on treatment day is probably fine to pro ( Full Answer )

What does a increased liver function low white blood cell count and low platelet count mean?

\nIt means something is wrong with your liver. You could have a disease like hepatitis a, b, or c, or liver cancer, or be on chemotherapy or be taking some medicine that affects your liver or have recently eaten something that disagreed with you and made you really sick so the poison has not yet lef ( Full Answer )

What are the reasons for low platelet count?

I was diagnosed with ITP idothrombocytopeniapurpura - it was a condition where my spleen was keeping my platelets. My platelet count was down to 3,500. After failed treatment with steroids, my spleen was removed and all is well. I am asymptomatic.

What does low blood platelets mean?

Thrombocytopenia, the name for low blood platelets, results in your blood not clotting, or not clotting as well as it should. It has several causes, and a person whose blood is not clotting as it should needs to see a doctor so the cause can be determined.

Is a 500 platelet count high?

A normal platelet count is between 150,000 - 400,000 platelets per microliter (mcL). Some labs represent this number as 150-400. Depending upon how they represent their findings your platelet count may be either high (500,000), or may be very low (500 as shown). Most labs will show an H or L next ( Full Answer )

Is 128 a low count for platelets?

I belive normal range is from 100,000-500,000, that is on the lower end of the spectrum but probably nothing to worry about. Although you should talk to your Dr. about it. There are many things that cause low platelets.

What does a low MCHC count mean-31.7?

bordeline of macrocytic anemia, which could be a folic aciddeficiency, liver disease, hereditary spherocytes or B-12 deficiency

Platelet count 113 what does it mean?

Platelet count of 113 (or 113,000 more properly) is indicative of mild thrombocytopenia. It should be monitored, but physicians generally don't become concerned until platelet counts are much lower.

What causes you to have a low platelet count in your blood?

A low platelet count, or what is called thrombocytopenia, can have many causes. There are conditions such as ITP, idiopathic thrombocytopenic purpura to more benign causes. Further testing may be needed, depending on how low your platelet count is. Consult your physician.

What does in mean if you have low red blood count?

a low red ount means that you have fewer numbers of red blood cells (RBC) per volume of blood than is normal.. "normal" will vary slightly from lab to lab, based on the equipment used, but normal ranges are listed below. If you have a level lower than the range listed, the main concerns a Doctor w ( Full Answer )

What is a low mean platelet volume?

The mean platelet volume measures the size of the platelets. This figure will be low when there is aplastic anemia, myelosuppression as a result of chemotherapy, in Wiskott-Aldrich syndrome, sarcoma of the bone since blood cells are manufactured in the bone marrow, and a couple of other condition ( Full Answer )

What are the symptoms of low platelet count?

Low platelet count leads to petechial hemorrhages. They can be seen at the hair roots. Later on you can have bleeding gums and bleeding through your nose. There can be vomiting of blood and bloody diarrhoea.

What does low liver enzyme count mean?

Most of the time it means that the enzymes in your liver which help the liver filter your blood, are decreasing their numbers due to virus or a serious medical condition

Is 100 a low platelet count?

>Platelets are commonly known as thrombocytes. >They are responsible for blood clotting process. >Therefore, platelets are inevitable. >Normally, the platelet count should be more than 1.5 lacs in an average human. >The platelet count 100, described in this question is very low as compared to norma ( Full Answer )

What does high lymphocyte and high platelet count mean?

A high lymphocyte and platelet count could indicate that you aresuffering from some sort of infection, as viruses will cause thesenumbers to be higher. More serious problems that can be indicatedby high counts are cancer and diseases of the bone marrow.

Is 23 low for a platelet count?

It actually is low for a platelet count just came from the doctor two days ago and mine was at 23 the put me on on steriods for four days to bring it up will update when i find out if it brought them up

What does a low MCHC count mean 317?

recent mchc slightly low at 317 also b12 has been slightly low at184 and also had bowel lesion removed september last year,tubullovillous adenema with mild dysplasia - could all these berelated?

What does low rbc count means in hematology?

It means low red blood cell count. You have less erytrocytes than a normal human. This doens't have to be serious. If it gets serious, you likely suffer from anemia (The haemoglobin test is more reliable for this).

Is platelet count 480 high or low?

It's considered high, but the range varies by technique and instrument calibration. It's about 80 points above the high normal range, which may be interpreted by your doctor as high normal, or abnormal depending on your medical history and other CBC results.

What are the risks of having a low platelet count?

Platelets are used by the body to form blood clots to prevent the body from bleeding. This means that a low platelet count can, in some cases cause increased blood loss after cuts or abrasions as the wound does not heal as quickly.

What is the significance of a low platelet count?

A low platelet count generally puts an individual at high risk of bleeding, or hemorrhage. The underlying cause of a low platelet count could be several diseases ranging from a something benign to HIV or leukemia.

What does having low blood count mean?

Having a low blood count means your blood is low on one of it's cell types. The symptoms are different depending on which, for example a low red cell count makes you anaemic and a low white cell count makes your immunity system drop.

What does a platelet count of 13 mean?

A platelet count of just 13 is dangerously low. Hemophiliac patients have low platelet counts. It means that you may bleed too much. If you have a platelet count of 50,000 or less, then you need to know what to do if you bleed and what not to do to prevent from bleeding.. Platelets help blood c ( Full Answer )