It means How are your grandparents?
"Como estan" in Spanish translates to "how are you" in English. It is a common greeting phrase used to inquire about someone's well-being or to ask how they are feeling.
It means "and my aunt and my cousins, how are they?" in English.
how are the girls -- How are they (all boys or a mixture of girls and boys)?
That sentence seems to be in "Text speak". It should read "¿Que haces? ¿Cómo estan?" This means "What are you doing? How are you (all)?
they are in
"Están" means "they are".
"The grandparents' house"
"Estan" from Spanish means "They are". It is the third-person, plural, conjugated form of "estar" ("to be").
"Como esta" translates to "how are you" in English.
Estan= to be
'como es' means 'how is'
it means: why not