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It is simply the duration methadone remains active in your system. It does not necessarily refer to just the euphoric effects. AS you probably know, methadone has the longest half-life of all synthetic opiates.

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Q: What does half life mean with methadone?
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The half life of methadone is 24 to 36 hours depending on metabolism.


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caffeine will increase metabolism. so yes it can drop the half life the methadone although more then likely, it will not be a significant amount.


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The answer to your question is yes and no. Yes, you can get a blackout when you take alcohol and methadone together. And no, methadone is not the cause of a blackout. If you get a blackout it is strictly from the Alcohol consumption. Of course, methadone will increase your level of intoxication. But if you blackout on methadone, you are either dead or overdosing. Methadone is a very dangerous drug and has an incredibly long half-life. I do NOT recommend mixing methadone and any other drug. If you are going to drink while on methadone, do so in moderation.


What is the shelf life of methylphenidate?

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How come when you quite taking methadone it still came up in a ua 1 week later?

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How does it take 250Mg of methadone to leave your system?

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