Translation: How are you, sister?
It should be noted that the construction of this sentence would sound odd to Spanish speakers because, usually, a sister (to whom you are related) would be addressed with the "tú" form, not the "Ud." form. (i.e. Hermana, ?cómo estas?)
como esta usted means how are you. It is very familiar manner to ask.
Apparently, it is a response to a "How are you?" question. "Muy bien, y usted como esta?" means "Very well, and you, how are you?"
I think you mean como estas. Como estas translates to how are you in Spanish.
"¿Cómo está usted?" is a Spanish phrase that means "How are you?" or "How do you feel?" It is a formal way to inquire about someone's well-being or current state.
This life is as good as you make it.
"¿Cómo está usted, señor?" is Spanish for "How are you, sir?" It is a polite way to inquire about someone's well-being.
"¿Cómo está usted?" in Spanish translates to "How are you?" in English. It is a formal way of asking someone about their well-being or current state.
La hermana esta enojada
"Como esta" translates to "how are you" in English.
As you, sir, are my lover. Did you mean: 'Como esta usted, mi querido?' (accents on first 'o' and 'a') = 'How are you, my beloved/love?'
Como esta la sopa? means How is the soup?
I don't know if you meant: "¿Está tu hermana?" (is your sister there?) or "¡Ésta, tu hermana!" (and your sister! Emphasising "your")