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It is a Pathological Condition in which the Immune System of human body fails, & the Immune cells cannot recognize the foreign Antigens (Microbes) or the neoplastic cells within the body leading to the Immune System Malfunctioning. Body responds nothing to the Allergens leading to severeness of the infection because the pathogenic infections are not halted or inhibited by Immune cells.
Immune tolerance or immunological tolerance is the process by which the immune system does not attack an antigen

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What are the types of immunological tolerance?

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Sir Frank Macfarlane Burnet won the Nobel Prize in Physiology or Medicine in 1960 for his work on acquired immunological tolerance. He shared the prize with Peter Medawar for their discovery of acquired immunological tolerance.


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Peter Brian Medawar won the Nobel Prize in Physiology or Medicine in 1960 for his discovery of acquired immunological tolerance, which revolutionized the understanding of the immune system and laid the foundation for organ transplantation. His research on immunological tolerance demonstrated how the body can accept foreign tissue without rejecting it, opening up new possibilities in transplantation medicine.


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