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What does permeability depend on?

Updated: 8/11/2023
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9y ago

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Permeability depends on membrane solubility and the presence of specific integral transport proteins.

Other factors such as pressure, concentration, and temperature of the molecules or solutes on either side, as well as the size of the molecules can also affect permeability.

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14y ago
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13y ago

Permeability depends on the size of the molecule, its shape, and whether it is hydrophilic or hydrophobic. Fick's Law can be used to determine how likely a molecule is to pass through the membrane by diffusion:

rate of diffusion = (concentration gradient x permeability of molecule x total surface area) / (molecular weight of molecule x thickness of membrane)

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15y ago

The concentraction grandient, the size of the materials, the size of passages through the membrane, the pressure on the solution on either side and the temperature can all play a role.

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13y ago

The size, charge, hydrophobicity and polarity of the molecule to permeate the membrane.

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13y ago

size, polarity, and charge

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