The nucleolus is the ribosome factory and also a multifunctional domain that plays an important role in nuclear organization and function. The nucleolus is assembled at the end of mitosis, is active during interphase, and dis-assembled in prophase. The nucleolar machineries of transcription and processing are inherited from parental to daughter cells through mitosis. The polymerase I transcription machinery is repressed during mitosis although assembled with ribosomal genes (rDNA). The repression of pol I transcription is achieved at the end of prophase and is maintained during mitosis through phosphorylation of transcription factors by cyclin-dependent kinase (CDK) 1. The nucleolar processing machineries relocalize from the nucleolus towards the periphery of all chromosomes in early prophase. The processing complexes remain associated with chromosomes until telophase and this chromosome association depends on CDK1 activity. In telophase, as a consequence of natural inhibition of CDK1 activity, pol I transcription is restored. The processing machineries are recruited to the sites of rDNA transcription after a temporary transit in foci assembled on the chromosome surface. These immobile foci called prenucleolar bodies (PNBs) could correspond to an assembly platform of processing complexes prior to recruitment to transcription sites. The contents of the PNBs are delivered to nucleoli with different kinetics and consequently PNBs have different life-times depending on their contents. Partly processed pre-rRNAs generated during prophase are inherited during mitosis and are found in PNBs. The possibility that the processing complexes forming PNBs can be nucleated by some pre-rRNAs passing through mitosis is proposed. Thereafter, nucleolar assembly is completed by cooperative interactions between chromosome territories. Thus the behavior of the nucleolus during mitosis illustrates the fact that the dynamics of nuclear organization at the beginning of interphase are integrated in a network of interactions and controls that is largely dependent on the coordination of mitotic events.
When the night has come And the land is dark And the moon is the only light we see No I won't be afraid No I won't be afraid Just as long as you stand, stand by me And darling, darling stand by me Oh, now, now, stand by me Stand by me, stand by me If the sky that we look upon Should tumble and fall And the mountain should crumble to the sea I won't cry, I won't cry No I won't shed a tear Just as long as you stand, stand by me And darling, darling stand by me Oh, stand by me Stand by me, stand by me, stand by me Whenever you're in trouble won't you stand by me Oh, now, now, stand by me Oh, stand by me, stand by me, stand by me Darling, darling stand by me Stand by me Oh stand by me, stand by me, stand by me
Stand to is when some one asks you to STAND and LISTEN
People stand, animals stand, trees stand, almost all living things stand.
what does ARAM stand for
Antonyms for stand are 'sit' and 'lie.'
Retort stand Tripod stand The answer is stand
sto, stare, steti, statum (to stand, stand firm, stand up.)
Stand is a verb. It describes an action. "Stand on the curb and wait for the bus." Stand is also a noun. "Take a stand for what you believe in."
refreshment stand or concession stand
What is OES? What does this stand for?What is OES? What does this stand for?
Stat means stand in latin.
The future tense of stand is "will stand."
It could stand for Scientiae Doctor.It could stand for Scientiae Doctor.It could stand for Scientiae Doctor.It could stand for Scientiae Doctor.It could stand for Scientiae Doctor.It could stand for Scientiae Doctor.
When the night has come and the land is dark; And the moon is the only light we see; No, I won't be afraid, Oh, I won't be afraid; Just as long as you stand, stand by me. So darling, darling, stand by me, oh stand by me; Oh stand, stand by me, stand by me; If the sky that we look upon should tumble and fall; Or the mountain should crumble to the sea; I won't cry, I won't cry, no I won't shed a tear; Just as long as you stand, stand by me; And darling, darling, stand by me; Darling, darling, stand by me; Whenever you're in trouble; Won't you stand by me, oh, stand by me
M stand for Maumoon and D stand for Dhanjassaa and P stand for Party (Maumoon Dhanjassaa Party)
Stand-Up Stand-Up - 1992 Stand-Up Stand-Up 3-12 was released on: USA: 7 August 1995
Stand here, I'll take your photograph.The teacher told me to stand outside.If you are too tired to stand then sit down.
Iron stand, it keeps the stand stable.
What does POS insurance stand for? What does POS insurance stand for?
The stand, the witnesses are called to the stand.
Stand to attention I am standing to attention stand here
People wait at the bus stand. The bus stops at the bus stand. The bus stand is near the meeting place. There is a ticket machine at the bus stand. There is a poster at the bus stand.
What does diamonds stand for