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How do Presynaptic neurons release neurotransmitters?
They don't, the neurotransmitters stay on either side of the synapse. Neurotransmitters are released when the synaptic vesicles fuse with the presynaptic neuron's membrane, so as to release them into the synaptic cleft.
What is the presynaptic neuron release neurotransmitters in response to an influx of?
Sodium ions
What is the difference between presynaptic and postsynaptic neurons?
Presynaptic neurons release the neurotransmitter in response to an action potential. Postsynaptic neurons receive the neurotransmitter (and can however become presynaptic to the next nerve cell, if the neurotransmitter has stimulated the cell enough).
Are the Autoreceptors are located on the presynaptic membrane?
Yes, Autoreceptors are located at the receptor site on the presynaptic neuron. They provide feedback on the amount of neurotransmitter release in the synaptic cleft in order to regulate its level through the activity of G proteins and second messengers.
These lipid molecules may function as retrograde neurotransmitters and allow the postsynaptic neuron to decrease release of neurotransmitter from the presynaptic neuron?
endocannabinoids
Presynaptic neurons release neurotransmitters by?
An action potential travels down the neuron and reaches the presynaptic knob. This causes the Calcium ion channels to open and allow an influx of calcium into the knob. The increased concentration of calcium causes the secretory vesicles within the knob to bind to the outer membrane and release their neurotransmitter (e.g. ACh) into the synaptic cleft.
What is The process by which the neurotransmitter substance leaves the presynaptic terminal button is called?
Leaves the presynaptic neuron, activates ion channel
Cocaine stimulates the synapses of specific neurons that release dopamine and other monoamines by?
blocking the dopamine or monoamine reuptake into the presynaptic axon ending
The botulinus toxin that causes botulism acts by?
Botulinus toxin blocks the release of acetylcholine from the presynaptic terminal. This is a total blockage of neuronal transmission.
What is an example of a presynaptic cell?
a neuron
Presynaptic inhibition is the opposite of?
Facilitation
What ion triggers the release of a neurotransmitter at the presynaptic membrane?
Calcium triggers synaptic vesicles to discharge the neurotransmitter into the synaptic cleft.
