It means :
How many brothers do you have ?
I only have sisters, but no brothers.
un frère = a brother 'de' is an article combien as-tu de frères = how many brothers do you have
The sentence 'Je n'ai pas de freres ni de soeurs' means I don't have any brothers nor any sisters. In the word-by-word translation, the personal pronoun 'je' means 'I'. The adverb 'ne...pas...ni' means 'not...nor'. The verb 'ai' means '[I] have'. The noun 'freres' means 'brothers'. And the noun 'soeurs' means 'sisters'.
"De tu" translates to "your" in English.
The indefinite article "de" in Spanish is analogous to the indefinite article "of" in English.
jubjb
Oui, j'ai des frères et des sœurs.
i am from...
from you
Of which or of what.
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De Veras means really? in English.