It means :
How many brothers do you have ?
I only have sisters, but no brothers.
un frère = a brother 'de' is an article combien as-tu de frères = how many brothers do you have
The sentence 'Je n'ai pas de freres ni de soeurs' means I don't have any brothers nor any sisters. In the word-by-word translation, the personal pronoun 'je' means 'I'. The adverb 'ne...pas...ni' means 'not...nor'. The verb 'ai' means '[I] have'. The noun 'freres' means 'brothers'. And the noun 'soeurs' means 'sisters'.
De tu means: of your in English.
The indefinite article "de" in Spanish is analogous to the indefinite article "of" in English.
jubjb
Oui, j'ai des frères et des sœurs.
Of which or of what.
i am from...
from you
what does tengo la clase de espanol en la primera hora mean in English
De is a preposition meaning of. It can also mean from, about, with, and as.