The worst to come so far from a tetanus vaccination is 50 children being paralyzed. Vaccines contain Mercury, animal cells and other chemicals other than the antitoxin.
Why was antitoxin given instead of a booster shot of tetanus toxoid?
There is no mention of the animal that requires these injections which makes it difficult to determine dosage. The use of antitoxin or toxoid is not always indicated, especially if the patient is current on the tetanus vaccine.
D. G. Evans has written: 'An investigation into the management of sauna suites' 'Persistence of tetanus antitoxin in man following active immunisation' -- subject(s): Vaccination, Tetanus, Tetanus antitoxin 'The protective properties of the alpha antitoxin and theta antihaemolysin occurring in Cl. welchii type A antiserum' -- subject(s): Gas gangrene antitoxin, Clostridium perfringens
No, the tetanus toxoid (routine vaccine) is not. However, the tetanus antitoxin for horses (which imparts antibodies directly to the horse that were produced by another horse) does. That is why the antitoxin comes with increased risk of adverse reaction and also why it doesn't provide prolonged protection. The toxoid causes the horse's body to develop it's own antibodies against the toxin that causes Tetanus while the antitoxin is pre-made antibodies.
Nicolaier was the one who discovered the anaerobic bacillus Clostridium Tetani in 1885. Almost simultaneously, in 1889, Kitasato, obtained the bacillus of tetanus in pure culture. Emil von Behring (March 15, 1854 - 1917) was the one, anyway, who provided the tetanus antitoxin. One of the major pharmaceuticals companies is named after his name.
Anaphylactic shock after being injected with tetanus antitoxin
Antitoxin is important.
Antitoxin refers to the antibody that counteracts a toxin.
No, and it never was. The tetanus vaccine only contains human immunoglobulin. There is something called tetanus anti-toxin that can be produced in horses or sheep. If you have a puncture wound and have never been immunized or it has been over 10 years since your last booster shot, your doctor may give you a shot of this antitoxin. It's like giving antivenom for a snakebite. This anti-toxin shot is NOT the same as the tetanus vaccine. It doesn't last long in your system, so it does not confer tetanus immunity.
after 30 minutes from the administration..
Toxin-antitoxin database was created in 2010.
Several important scientists made significant contributions to the control of tetanus. Arthur Nicolaier (1862-1942) discovered he tetanus bacterium in 1884. Three years later, while engaged in a study of disinfectants, German bacteriologist Emil von Behring noticed that the blood serum of tetanus-immune laboratory rats neutralized the anthrax bacteria. He set about isolating the substance that gave the rats resistance to the bacteria.In the Berlin laboratory of scientist Robert Koch, Behring joined with Japanese bacteriologist Shibasaburo Kitasato, the first person to isolate the tetanus bacterium in pure culture in 1889. He later isolated and described the bacteria that cause diphtheria, anthrax, and bubonic plague. Behring and Kitasato discovered that the presence of tetanus and diphtheria toxins in blood cause the blood to produce antitoxins that neutralize the poisonous substances. When they injected small amounts of tetanus toxin into animals, the animals produced antitoxins, which gave them immunity from the disease. Furthermore, blood serum containing antitoxins extracted from these animals and injected it into other animals, gave the new animals immunity to tetanus, as well.They called this procedure "blood serum therapy."Behring developed a way to produce antitoxin serum in guinea pigs, and later developed a toxin-antitoxin mixture which was an effective vaccine against tetanus. In 1893, French scientist, Pierre-Paul-Emile Roux (1853-1933), assistant to Louis Pasteur at the Pasteur Institute, developed improved procedures for using antitoxin serum to prevent as well as treat tetanus.