Name of the anticoagulant

Answer 1

Here are some anti-coagulant drugs:

1. Heparin

It is a naturally occuring coagulant and it binds to anti-thrombin III to increase its action of blocking the activity of thrombin and some other clotting factors. It can be given either subcutaneously or intravenously.

2. Warfarin

It is an oral anti-coagulant which inhibits the vitamin K dependent synthesis of calcium-dependent clotting factors II, VI, IX, and X. At least 4-5 days is needed for warfarin to become fully effective.

3. Anti-platelet drugs (eg. aspirin)

These drugs irrverisbly block the formation of thromoxane A2 in platelets by inhibiting cyclooxygenase (COX) enzymes. This produces an inhibitory effect on platelet aggregation.

4. Thrombolytic agents (eg. recombinant tissue plasminogen activator (rt-Pa)

These drugs are manufactured with recombinant biotechnology techniques and they have the same actions as natural tPa. The mediation dabigatran directly inhibits thrombin.

Answer 2

We should break this down into classifications of drugs -

Anti-platelet drugs

• Aspirin
• Plavix
• Ticlid - not used much anymore due to significant side effects

Anticoagulants

• Heparin
• Lovenox (and other low molecular weight heparin products)
• Coumadin

Direct Thrombin inhibitors

• Lepirudin
• Bivalirudin
• Argatroban

As far as outpatient use, the most common are aspirin, plavix, and coumadin.

Answer 3

A thrombus (plural thrombi), colloquially called a blood clot, is the final product of the blood coagulation step in hemostasis. A thrombus is an intravascular aggregate of fibrin and platelets, usually in laminated layers, that is attached to the vessel wall or valve. Thrombi are most often found in large and midsize arteries and less commonly in veins. With maturation, thrombi undergo organization and recanalization and may contain varying amounts of fibrous connective tissue or dystrophic mineralization. Thrombi are of clinical importance due to occlusion of vessels and loss of blood supply leading to infarction, particularly in organs that lack collateral circulation. Portions of thrombi may also break free and give rise to emboli, which may occlude distal vessels.

Heparin (hep) is a highly anionic glycosaminoglycan extensively used in clinics, mainly as an anticoagulant and also as an antiviral and anticancer agent. However, the number of antidotes for heparin-type drugs is quite limited: the one mostly used is protamine, a small arginine-rich nuclear protein. Considering the general drawbacks of using high-molecular-weight drugs, the search for alternative small molecules able to revert the anticoagulation effects of heparin is a hot topic in current research. Among these small molecules, probably surfen and ciraparantag (also named PER977) are the most representative examples. The chemical complexity of Heparinis also accompanied by high conformational flexibility in solution, complicating establishing a preferred three-dimensional structure by either experimental (X-ray diffraction, NMR) or theoretical (molecular modeling) approach. Overall, this makes the rational design of ligands against Hep an extremely challenging task..benchchem.

Answer 4

Heparin is an anticoagulant that has a short action of about 12 hours. Warfarin is the anticoagulant given for long term treatment. Hope this helps.

Answer 5

what is the name of the anticoagulant used to prevent thrombus or embolus

Answer 6

i believe it is coumadin

Answer 7

Cummiden, Warfarin and others.

Answer 8

Heparin sodium