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Brand name: Selgin

Active substance: Selegiline hcl

Packaging: blister sheet 10 x 5mg

Shipped from: India

Selegiline, also known as l-deprenyl, is an irreversible and (relatively) selective MAO-B inhibitor. Meta-analysis of published clinical trials confirms it offers a cheap, safe and effective symptomatic treatment of early Parkinson's disease. Selegiline may also be neuroprotective and act as an antidepressant.

Selegiline has immune-system-boosting and anti-neurodegenerative effects. Its use increases the level of tyrosine hydroxylase, growth hormone, cerebral nitric oxide and the production of key interleukins. Selegiline offers protection against DNA damage and oxidative stress by hydroxyl and peroxyl radical trapping; and against excitotoxic damage from glutamate. In addition, selegiline stimulates the release of superoxide dismutase (SOD). SOD is a key enzyme which helps to quench the production of damaging free-radicals. Potentially, selegiline may prevent or reverse iron-induced memory impairment. The deposition of excess iron in the brain is implicated several neurodegenerative diseases.

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