What happend on the 100th episode of Family Guy?

Answer 1

The 100th episode was Lois Kills Stewie.

Everyone is shocked that Stewie would try to murder Lois, but she insists that he is evil, and explains what happened; after being shot at and falling overboard, she was rescued by a merman, and became employed at a fat camp and later a diner, where she found a new boyfriend in a white supremacist also visiting the diner, as she had developed amnesia. She eventually regains her memory after being attacked at a supremacist rally, and returns to Quahog. While Lois explains her situation, Stewie escapes, captures and restrains his family when they return home, and shoots Cleveland dead when he visits. Stewie kidnaps Brian and forces him into driving him to the CIA, where he gains access to asupercomputer and takes control of the planet's power grid, thus dominating the world.

After Stewie implements numerous draconian laws, Lois becomes angered and prepares to assassinate him. Lois and Stewie engage in a fight at the Oval Office when she arrives; Lois eventually gains the upper hand and prepares to shoot Stewie, but she cannot bring herself to do so, since he is her own child. Stewie takes the opportunity to disarm her and prepare to kill, but is shot dead by Peter. They then start to cry over Stewie's dead body and are devastated. Just before Peter and Lois leave the room, it is revealed that much of what has happened was actually a computer simulation. Brian is upset the whole thing was a "dream sequence", although Stewie argues that a computer simulation is totally different. Stewie then claims that he is not ready to kill Lois....yet.