Generally speaking the surrender of Robert E. Lee to US General Grant is referred to as the surrender at the Appomattox Court House. Lee's surrender was the key which in all practical terms ended the US Civil War. Later other Southern armies would surrender.
The Confederate surrender at Appomattox Court House was in the year 1865, on April 9th.
Appomattox Court House
appomattox court house
Appomattox Court House
The surrender of the Army of Northern Virginia was at McLean House.
Appomattox Court House, Virginia
Appomattox Court House - it was barely a town (though it was more than a Court House!)
The surrender of the Army of Northern Virginia under Lee at Appomattox Court House.
Appomattux Court House
Appomattox Court House, Virginia
Appomattox Court House