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What happens in each of the five phases of cardiac muscle depolarization?
Wiki User
∙ 12y ago
PHASE0(RAPID DEPOLARIZATION)
due to opening of fast voltage gated sodium channels
PHASE1(INITIAL REPOLARIZATION)
due to closure of sodium channels while loss of potassium is goingon ,making the cell polarized.
PHASE2(PLATEAU)
due to opening of calcium channels. influx of calcium neutralizes the effect of out going potassium so prolonged plateau is achieved.
PHASE3(FINAL RE POLARIZATION)
due to closure of calcium channels and continue loss of potassium makes the inside of cell more negative resulting in polarization.
PHASE4(RMP)
eventually cell returns to resting membrane potential due to K efflux and cell is ready for next cycle
Wiki User
∙ 12y ago
Wiki User
∙ 12y agoContraction (systole) follows.
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