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T4 is storage hormone and is inactive. It is converted to T3, which is the active form of the hormone that your cells use. The tests FT3 and FT4 tell how much of the hormone is in your blood, unbound to other proteins and hormones so they can be converted or utilized by the body. TSH is the hormone from your pituitary gland near your brain that tells your thyroid to produce more hormone.

A low FT4 and FT3 will result in an elevated TSH, indicating hypothyroidism - your thyroid isn't producing enough thyroid hormone.

A high FT4 and FT3 will result in a decreased TSH, indicating hyperthyroidism - your thyroid is producing too much thyroid hormone.

Normal levels of FT3 and FT4 may indicate several issues, including a problem with the pituitary gland itself; or a change in thyroid supplementation and testing that has occurred before TSH levels have had an opportunity to reflect those changes.

There are other causes of hormonal abnormalities, but an endocrinologist will know the correct tests to use to determine a diagnosis and potential treatment for abnormalities that are found.

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Q: What happens when FT3 is 2.72 and FT4 is 1.05 and TSH is 7.18?
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