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The actually effect of eating grapefruit is not clearly defined, but it is documented to increase the total amount of some drugs that enters your bloodstream. Therefore it is basically raising your effective dose without your doctor's consent or knowledge. It is not a predictable increase, but could double it or more.

It is best to stay away from grapefruit or grapefruit juice completely, because it can complicate or invalidate any attempt to define the dosage that works best for you.

When on prescription medication, advise your doctor before making substantial changes to your diet.

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Q: What happens when you drink grapefruit juice with Seroquel XR 50?
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