1. damage to the endothelium due to hypertension creating turbulent blood flow (fatty Streak) 2. Oxidised LDL moves in
3. Foam cells move in. these include macrophages which act to consume the LDL
4. Cytokines released by macrophages result in smooth muscle proliferation
5. Formation of a fibrous cap
You can then get rupture of the plaque and then this causes hear attacks.
Pathogenesis is the medical term meaning process that initiates a disease.
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The process towards canonization usually begins on the local diocese level or, if the person was a member of a religious order, the religious order initiates the process.
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