What investigation cannot perfectly reproduce the condition of the natural world?

What is trna and what does it function? How can a worldwide increase in temperature affect organism? What happened to temperatures after mount Pinatubo? What is the latitude and longitude of Mauna Kea? Which body part controls the function of other body parts? What is ornithine decarboxylase? What does Mercury look like and how far away from the sun is it? What is the prescribed standard for noise level in industrial area during day time? How is an organism made up of cells that have a membrane-bound nucleus? How big is 70mm in centimetres? What is the name of the process where two atoms combine to make a larger one releasing energy? How do you measure area of square and rectangle? What is the hardes question on earth? Is venus covered in an orange dust made of iron and oxygen particles? What is the weight of javelin? How did dr. Isaac Cline help to save lives before the hurricane hit? Why did the living rejoice when the order came tho throw out the corpses? What is the distance between 45 degrees north and 45 degrees 30 minutes north? When should you know the difference between living and non living things? What philosophy states that the universe consists of nothing but matter and energy and has no spititual and supernatural aspects?

What investigation cannot perfectly reproduce the condition of the natural world?