"East" and "(he, it, one, she) is" are English equivalents of the French word est. Context makes clear which translations suits. The pronunciation will be "est" for the direction (case 1) and "ey" for the state of being (example 2) in French.
Est le... in French means "Is the..." in English.
Qui est...? in French is "Who is...?" in English.
Est-il moche? in French is "Is he ugly?" in English.
Comment est-il? in French means "How is he/it?" in English.
Comment est votre...? in French means "How is your...?" in English.
Est-ce que...? in French means "Is it that...?" in English.
is that / is this / is it ...
Qui est de Paris? in French is "Who is from Paris?" in English.
"who is it ? who is he ? who is she ?"
Ton français est excellent! in French means "Your French is excellent!" in English.
Quel est ton prénom? in French means "What is your first name?" in English.
Qui est le meilleur? in French means "Who is the best?" in English.