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Histidine is one of the amino acids present in the actin and myosine of muscles. As the muscles contract, some of the histidines are released from the muscle in to the blood. Having been methylated, these histidines are converted to 3-methylhistidnie.

Urinary excretion of 3-methylhistidine is a marker of muscle mass in laboratory analyses.

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Q: What is 3-Methylhistidine?
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