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Mary Shelley's most famous work is a novel called Frankenstein which coincidently she wrote after having a nightmare.

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Mary Shelley's most famous work is "Frankenstein; or, The Modern Prometheus," which was first published in 1818. The novel tells the story of a scientist who creates a living being using various body parts, leading to tragic consequences.

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Q: What is Mary Shelley's most famous work?
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