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What is an allantoinase?
In biochemistry, an allantoinase is an enzyme which produces allantoate as part of purine metabolism.
How allopurinol acts toward formation of uric acid?
Allopurinol is a structural isomer of hypoxanthine (a naturally occurring purine in the body) and is an enzyme inhibitor, inhibiting xanthine oxidase. Xanthine oxidase is responsible for the successive oxidation of hypoxanthine and xanthine resulting in the production of uric acid, the product of human purine metabolism. In addition to blocking uric acid production, inhibition of xanthine oxidase causes an increase in hypoxanthine and xanthine, which are converted to closely related purine ribotides adenosine and guanosine monophosphates. Increased levels of these ribotides causes feedback inhibition of amidophosphoribosyl transferase, the first and rate-limiting enzyme of purine biosynthesis. Allopurinol therefore decreases both uric acid formation and purine synthesis. (source wikipedia)
What is the enzyme ADA?
Adenosine deaminase is an enzyme(EC3.5.4.4) involved in purine metabolism. It is needed for thebreakdown of adenosinefrom food and for the turnover of nucleic acidsin tissues.
What is endogenous purine nucleoside?
Endogenous purine nucleosides are molecules that naturally occur in the body and play important roles in processes like DNA and RNA synthesis, energy metabolism, and cell signaling. Examples include adenosine and guanosine. These molecules are essential for various cellular functions and are derived from purine bases like adenine and guanine.
What is transversion mutation?
A transversion mutation is a type of point mutation where a purine base is substituted for a pyrimidine, or vice versa. This type of mutation results in a change in the base pair from a double-ring structure to a single-ring structure, potentially causing changes in the amino acid sequence during protein synthesis.
What is the significance of purine numbering in the context of nucleotide structure and function?
The purine numbering system is important in understanding the structure and function of nucleotides because it helps to identify specific atoms within the purine molecule. This numbering system allows scientists to accurately describe and study the interactions and chemical properties of nucleotides, which are essential building blocks of DNA and RNA. By using the purine numbering system, researchers can better understand how nucleotides function in processes such as DNA replication and protein synthesis.
Is purine aromatic?
Yes, purine is aromatic.
What is the purine content of campari?
what is the purine content of Campari.
What is an example of purine?
Adenine and guanine are both examples of purine.
Description of Low purine and purine restricted?
Low purine diet means to avoid internal organs,sardines and legumes.
Will a purine base bond with another purine?
no.because there is not enough space to bind two purine bases.
What does HPRT do?
HPRT catalyzes a reaction that is necessary to prevent the buildup of uric acid, a nitrogenous waste product that is ordinarily excreted from the body through the kidneys. A severe mutation in the HPRT gene leads to an absence of HPRT enzyme activity =
