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Named for the Greek words for iron and germ, sideroblastic anemia is one of the principal types of iron-utilization anemia
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Who does Sideroblastic Anemia affect?
Sideroblastic anemia is a disease of adults.
How is sideroblastic anemia cured?
Acquired sideroblastic anemia may be cured when the condition that causes it is treated or removed.
How is Sideroblastic Anemia caught?
Sideroblastic anemia can be inherited, but the disease is usually acquired as a result of illness or exposure to toxic substances.
What are complications of sideroblastic anemia?
Possible complications of sideroblastic anemia include: congestive heart failure, diabetes mellitus, enlargement of the liver and spleen, formation of liver nodules and scar tissue,
What is Sideroblastic anemia associated with?
Sideroblastic anemia is also associated with: leukemia, lymphoma (cancer of the lymph glands), myeloma (cancer of the bone marrow), rheumatoid arthritis, and other inflammatory diseases
When is oral pyridoxine used to treat sideroblastic anemia?
In rare instances, treatment with oral pyridoxine (a B-complex vitamin) benefits patients whose sideroblastic anemia was present at birth. This treatment improves the condition of some patients but does not cure the anemia.
When does sideroblastic anemia require transfusions?
the cause of a patient's anemia cannot be determined, blood transfusions may be necessary. Medications are prescribed to stimulate excretion or excess iron that accumulates as a result of these transfusions.
How is sideroblastic anemia diagnosed?
Blood tests are used to examine the appearance and other characteristics of red cells and to measure the amount of iron in the blood. Bone marrow biopsy is also used
What is treatment for macrocytic anemia?
Macrocytic anemia is a condition where the red blood cells are larger than they should be. They are usually larger and there usually is a lower number than there should be.
What happens in Sideroblastic Anemia?
Abnormal, iron-saturated red cells are present in the blood of people who have this disease. Although the iron circulates normally from the plasma to the bone marrow, where new red blood cells are created, it is not properly incorporated
When was sickle cell anemia discovered?
Sickle cell anemia was discovered in the 1870's and carried many names, but 1922 it was officially named sickle cell anemia.
Common causes of microcytic hypochromic anemia?
In very rare cases this combined affect is documented in the paper: "Identification of a SLC19A2 nonsense mutation in Persian families with thiamine-responsive megaloblastic anemia" by Setoodeh A et al 2013.
