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I think these are magnetic particles coated with streptavidin so that once anything conjugated with biotin binds streptavidin, the whole bound complex can be selectively removed using some sort of magnet.

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14y ago

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What is the charge of streptavidin?

Streptavidin has a neutral charge at pH 7 due to an equal number of positively charged amino acids (Lysine and Arginine) and negatively charged amino acids (Aspartic acid and Glutamic acid) present in its structure.


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Streptavidin beads can be used in protein purification by binding to biotinylated proteins. The strong interaction between streptavidin and biotin allows for efficient isolation of the target protein from a complex mixture. This method is commonly used in research and biotechnology to purify proteins for further analysis or experimentation.


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