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Why benzethonium chloride is used?
Benzethonium chloride is commonly used as a preservative and antimicrobial agent in various personal care products, such as hand sanitizers, disinfectants, and skin antiseptics. It is effective in preventing the growth of bacteria, fungi, and viruses, making it a popular choice for products aimed at promoting hygiene and preventing infections.
Is Sodium Benzoate the same thing as Benzethonium chloride chloride?
No, they are very different substances.
Can Benzethonium chloride be used safely as a mouthwash to kill chronic bad breath due to tonsil stones?
Visit any website about tonsil stones, and remedies abound. One such remedy is grapefruit seed extract, also identified as GSE. As told to readers, GSE, when added to water creates an effective gargle that can attack bacteria and calcium deposits linked to the formation of tonsil stones. Its anti-microbial and anti-fungal properties are thought to bring this benefit.The extract may also contain the synthetic ingredient benzethonium chloride. This ingredient is not extracted from the seed itself, but rather by the way it is processed. Apparently, though it is touted as a "natural cure," this synthetic ingredient, along with its anti-microbial and anti-fungal properties, are what make it work for tonsil stone relief. The inclusion of benzethonium chloride in GSE has made supporters of organic natural medicines fight against the extract ever carrying an organic label. Unfortunately, studies have also found that GSE without the ingredient are less effective for treating tonsil stones.Here is a link to a U.S. Department of Agriculture report about the occurence of benzethonium chloride in commercial grapefruit extract:So ...if inorganic grapefruit seed extract is effective in treating and preventing tonsil stones, is its synthetic ingredient benzethonium chloride safe, especially when ingested orally as a gargle? It is also used in cosmetics, detergents and deoderants afterall.READ: "It is safe at concentrations of 0.5 percent in COSMETICS applied to the skin. A maximum concentration of 0.02 percent is safe for cosmetics used in the EYE AREA."Some sites report that ingesting (that would be swallowing) 1-3 grams of benzothonium chlorides could be fatal:lSo those interested in this remedy might consider that finding GSE in its purest form may not do the trick.In conclusion, there is not enough evidence to support the use of the word "safe" in relation to the question
What are the precautions associated with using grapefruit seed extract?
The following is a statement received in email from Nutribiotics: Newsgroups, email groups, and web sites have received postings to the effect that GSE contains triclosan, benzethonium chloride, or methyl paraben. The reason is that GSE is very similar in molecular weight to both benzethonium chloride and triclosan, both of which are effective disinfectants, but are toxic to human and animal life. Some tests for benzethonium chloride and methyl paraben come up positive (which is more correctly called a "false positive") and the same is happening for triclosan. Meanwhile, Citricidal (the brand of GSE NutriBiotic uses) has been tested for the presence of these toxins by independent labs and has been proven clean. (Ex: Weston Gulf Coast Laboratories, Inc., University Park, IL, test completed in March of 1992. Tested for heavy metals, cyanides, pesticides and PCBs, and benzalkonium chloride. Results: None Detected.) In fact, the accusations about benzethonium chloride became so frequent that Citricidal began specifically testing each batch of GSE for its absence and providing a Certificate of Analysis to that effect. The truth is, Citricidal is not only effective, it has been in use for over 25 years. If these allegations had any validity, there certainly would be a history of complaints and judgments against the product, and it would have been removed from the market many years ago. The US FDA made inspections of the NutriBiotic manufacturing facility back in the 1990's and found no chemical preservatives; and the formula is the same today. Such rumors are false, and are not a threat to those armed with accurate information. The reports are certainly bothersome, but they have produced "false positives", not accurate profiles. The vast body of evidence from many years of use by thousands of satisfied consumers, doctors, manufacturers, and veterinarians speaks most loudly against such reports. Citricidal and NutriBiotic GSE are proven safe and effective products.
Is it safe to use bactine on a navel piercing?
Chemicals WILL NOT make you heal faster! Quite the opposite in fact, chemicals of any kind will upset the balance within your newly forming cells and create a condition in which your piercing will heal tremendously slow, if ever. Therefore, DO NOT USE any product marked for "external use only" including, but not limited to: Proven, rubbing alcohol, Hydrogen Peroxide, Bactine and Ear Care Solutions, benzethonium chloride, Antibacterial soaps, such as Dial, Soft Soap, etc., Neosporin or any other petroleum-based ointment such as betadine or Hibiclens.REMEMBER IF YOU CAN'T PUT IT IN EYES DON'T PUT IT IN YOUR PIERCING!PRODUCTS YOU CAN USESALINE SOLUTION: Saline is the key to quick healing! It's PH balanced to our bodies. The easiest and most accurate way to acquire saline is in the form of saline solution for contact lenses, preferably the sterile type in a pressurized can. DO NOT use multi- purpose solutions or wetting/soaking solutions, they contain an enzyme and are not the same as saline solution.NON-IODIZED SEA SALT: Non-iodized sea salt will always state on the package "this salt does not contain iodine, a necessary nutrient." Check the label before you purchase. DO NOT USE table salt or Epson salt.
What is cetrimonium?
Quaternary ammonium compounds are any of a group of ammonium salts in which organic radicals have been substituted for all four hydrogens of the original ammonium cation. They has a central nitrogen atom which is joined to four organic radicals and one acid radical. The organic radicals may be alkyl, aryl, or aralkyl, and the nitrogen can be part of a ring system. They are prepared by treatment of an amine with an alkylating agent. They show a variety of physical, chemical, and biological properties and most compounds are soluble in water and strong electrolytes. Such compounds include * Benzalkonium Chloride ( CAS RN: 8001-54-5) * Benzethonium Chloride CAS 121-54-0 * Cetalkonium Chloride( CAS 122-18-9) * Cetrimide ( CAS 8044-71-1) * Cetrimonium Bromide ( CAS 57-09-0) * Cetylpyridinium Chloride (CAS 123-03-5) * Stearalkonium Chloride ( CAS 122-19-0) They have properties of disrupting micro-organisms' cell processes and surfactants. These compounds are used as * Active Ingredient for Conditioners * Antistatic Agent * Detergent Sanitisers * Softner for textiles and paper products * Phase Transfer Catalyst * Antimicrobials * Disinfection Agents And Sanitizers * Slimicidal Agents * Algaecide * Emulsifying Agents * Pigment Dispersers
What is Cetrimonium chloride?
Quaternary ammonium compounds are any of a group of ammonium salts in which organic radicals have been substituted for all four hydrogens of the original ammonium cation. They has a central nitrogen atom which is joined to four organic radicals and one acid radical. The organic radicals may be alkyl, aryl, or aralkyl, and the nitrogen can be part of a ring system. They are prepared by treatment of an amine with an alkylating agent. They show a variety of physical, chemical, and biological properties and most compounds are soluble in water and strong electrolytes. Such compounds include * Benzalkonium Chloride ( CAS RN: 8001-54-5) * Benzethonium Chloride CAS 121-54-0 * Cetalkonium Chloride( CAS 122-18-9) * Cetrimide ( CAS 8044-71-1) * Cetrimonium Bromide ( CAS 57-09-0) * Cetylpyridinium Chloride (CAS 123-03-5) * Stearalkonium Chloride ( CAS 122-19-0) They have properties of disrupting micro-organisms' cell processes and surfactants. These compounds are used as * Active Ingredient for Conditioners * Antistatic Agent * Detergent Sanitisers * Softner for textiles and paper products * Phase Transfer Catalyst * Antimicrobials * Disinfection Agents And Sanitizers * Slimicidal Agents * Algaecide * Emulsifying Agents * Pigment Dispersers
What is the use of acetic acid in a pharmaceutical company?
One use is described in the following NDC-approved packaging label (NDC # 60432-741-15) for a particular formulation using what is known as "glacial acetic acid": acetic acid (Acetic Acid) solution[Morton Grove Pharmaceuticals, Inc.]= DESCRIPTION = Acetic Acid Otic Solution, USP is a nonaqueous solution of glacial acetic acid, USP (2%), in a propylene glycol vehicle containing benzethonium chloride, USP (0.02%); propylene glycol diacetate, NF (3%) and sodium acetate, USP (0.015%). It may also contain citric acid, USP. The molecular formula for acetic acid is CH3COOH, with a molecular weight of 60.05. The structural formula is: Acetic Acid Otic Solution is available as a nonaqueous otic solution buffered at pH 3 for use in the external ear canal. = CLINICAL PHARMACOLOGY = Acetic acid is anti-bacterial and anti-fungal; propylene glycol is hydrophilic and provides a low surface tension; benzethonium chloride is a surface active agent that promotes contact of the solution with tissues. = INDICATIONS AND USAGE = For the treatment of superficial infections of the external auditory canal caused by organisms susceptible to the action of the antimicrobial. = CONTRAINDICATIONS = Hypersensitivity to Acetic Acid Otic Solution or any of the ingredients. Perforated tympanic membrane is considered a contraindication to the use of any medication in the external ear canal. = WARNINGS = Discontinue promptly if sensitization or irritation occurs. = PRECAUTIONS = Transient stinging or burning may be noted occasionally when the solution is first instilled into the acutely inflamed ear. Safety and Effectiveness in pediatric patients below the age of 3 years have not been established. = ADVERSE REACTIONS = Stinging or burning may be noted occasionally; local irritation has occurred very rarely. = DOSAGE AND ADMINISTRATION = Carefully remove all cerumen and debris to allow Acetic Acid Otic Solution to contact infected surfaces directly. To promote continuous contact, insert a wick of cotton saturated with the solution into the ear canal; the wick may also be saturated after insertion. Instruct the patient to keep the wick in for at least 24 hours and to keep it moist by adding 3 to 5 drops of the solution every 4 to 6 hours. The wick may be removed after 24 hours but the patient should continue to instill 5 drops of Acetic Acid Otic Solution 3 or 4 times daily thereafter, for as long as indicated. In pediatric patients, 3 to 4 drops may be sufficient due to the smaller capacity of the ear canal. = HOW SUPPLIED = Acetic Acid Otic Solution USP, 2% is supplied in 15 mL measured drop, safety-tip plastic bottles. Store at controlled room temperature, 15 °-30 °C (59 °-86 °F). KEEP CONTAINER TIGHTLY CLOSED Rx Only Product No.: 8741 Manufactured By:Morton Grove Pharmaceuticals, Inc.Morton Grove, IL 60053 A50-8741-15REV. 3-04 =========================================== The following (apparently rather dated) excerpt from the British Pharmaceutical Codex describes other uses. (The authenticity of the following excerpt, which was found at:http://www.henriettesherbal.com/eclectic/bpc1911/acidum-acet.htmlwas not independently researched). Published by direction of the Council of the Pharmaceutical Society of Great Britain, 1911. Related entry: Vinegar - VinegarsOther tomes: Ellingwood - King's Acetic acid is obtained by the destructive distillation of wood, or by the oxidation of alcohol. It should contain 33 per cent. by weight of real acid, CH3COOH, and may be purified by distilling over potassium permanganate. It occurs as a clear, colourless, pungent liquid, miscible with water and alcohol in all proportions. Specific gravity, 1.044. Acidum Aceticum, U.S.P., contains 36 per cent. by weight of absolute acetic acid, and has a specific gravity of 1.045 at 25°. Action and Uses.-Acetic acid is oxidised in the body and is excreted in the urine as carbonate; it is, therefore, mildly diaphoretic, diuretic, and expectorant. It is administered in mixtures in the form of the diluted acid, or as oxymel, or oxymel of squill. Applied externally, it has an irritant action, and it is therefore used in liniments. The well-diluted acid is employed as a gargle (1 in 30). Acidum Aceticum Dilutum is used to sponge the skin in fevers, and as a lotion for the scalp. Acetic acid has been employed as a menstruum for making non-alcoholic preparations resembling tinctures. It is an efficient agent for the exhaustion of many drugs, and preparations made in this way are known as "acetracts"; their acidity and sour flavour are, in some instances, objections to their use. Acetic acid is incompatible with alkali salts, hydroxides, carbonates, bicarbonates, salicylates, and benzoates. ; Acetum Odoratum, B.P.C.-TOILET VINEGAR. : Acetic acid (1 in 8), with odorants. Used as a deodorant by sprinkling about the sick room; it is mixed with water for washing in the bath or hand-basin; a few drops are inhaled from the handkerchief as a restorative, or applied to the forehead to relieve headache. ; Acidum Aceticum Dilutum, B.P.-DILUTED ACETIC ACID. : Acetic acid (33 per cent.), 12.5; distilled water, sufficient to produce 100. ; Acidum Aceticum Dilutum, U.S.P.-DILUTED ACETIC ACID, U.S.P. : Acetic acid (36 per cent.), by weight, 20; distilled water, 100. C2H4O2 = 60.032. Glacial acetic acid may be obtained by the distillation of dried sodium or calcium acetate with strong sulphuric acid. It should contain 99 per cent. by weight of real acid, CH3COOH. The acid is also official in the U.S.P. It occurs as a clear colourless liquid, or colourless, crystalline mass, with a strong pungent odour. It is crystalline at low temperatures, and the crystals melt again at about 14.8°. A variety of glacial acetic acid is in commerce, melting at 10°. The official melting-point for glacial acetic acid (15.5°) corresponds to a stronger acid than 99 per cent. Specific gravity, 1.058 (about 1.049 at 25°), increased by the addition of 10 per cent. of water. Boiling-point not less than 117°. Action and Uses.-Glacial acetic acid is a rubefacient, vesicant, or caustic, according to the length of time it is in contact with the skin. Its use requires caution, owing to its tendency to spread. It is chiefly employed as a mild caustic for destroying warts, corns, etc. When inhaled by the nostrils, glacial acetic acid induces a reflex stimulation of the medullary centres. It is therefore employed in this manner as a restorative and stimulant in cases of fainting. In cases of poisoning by glacial acetic acid large draughts of water containing soap, washing soda, magnesia, or chalk, and oil, or gruel should be given. ; Acidum Aceticum Aromaticum, B.P.C.-AROMATIC ACETIC ACID. Syn.-Aromatic Vinegar. : Glacial acetic acid, with odorants. Employed as a restorative by inhaling from a small saturated sponge contained in a vinaigrette. It should be distinguished from toilet vinegar (see Acetum Odoratum).
