A biomacromolecule is any macromolecule which is of biological origin.
The type of biomacromolecule that contains paired bases is deoxyribonucleic acid (DNA). In DNA, the bases adenine (A) pairs with thymine (T), and cytosine (C) pairs with guanine (G), forming the rungs of the double helix structure. This base pairing is crucial for the replication and transmission of genetic information.
Lipids are a class of chemical compounds, all lipids are compounds not all compounds are lipids. Chocolate chip is class of cookies, not all cookies are chocolate chip. lipids are "fats" and "oils" they are triglycerides.
It could be practically any molecule. Some of them are more suspicious because they for example damage DNA, but carcinogens may for example somehow destroy the repairing mechanism of DNA aberation which is rather a complicated process and one cannot tell about any molecule how it will behave in contact with any particular biomacromolecule.
Proteins are the body building biomacromolecule seen in the body. Proteins are biopolymers of the basic twenty aminoacids through peptide bonds. Proteins have different levels of structure - Primary, secondary, tertiary (single peptide protein) and quarternary structure (Subunit proteins). Proteins are either globular or fibrillar in nature. Proteins can be classified based on the conjugation and function as follows: * Receptor protein - Photoreceptor Rhodopsin * Nucleoprotein - Histones * Metalloprotein - Haemoglobin, myoglobin - respiratory pigments * skeletal and muskular proteins - actin, myosin, dystrophin * Membrane protein - seen in lipoprotein membrane, RBCs as antigens * Facilitating proteins - Chaperones or heat shock proteins * Structural proteins - keratin, collagen * Immunoproteins - immunoglobulins * Enzymes and hormones - trypsin, insulin
Many factors can contribute to affect the bioavailability of the orally administered drugs. Briefly, these includes gastric emptying rate, intestinal transit time, hepatic first pass metabolism, and gastrointestinal and hepatic blood flow etc. apart from these factors, disease conditions, diet and dosage form also contribute in alteration of the bioavailability of the drugs.