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What is a coagulation cascade in a partial thromboplastin time test?

Updated: 8/19/2019
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GaleEncyofMedicine

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13y ago

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A coagulation cascade is the sequence of biochemical activities, involving clotting factors, that stop bleeding by forming a clot.

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Q: What is a coagulation cascade in a partial thromboplastin time test?
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How would you describe the partial thromboplastin time test analysis?

The PTT test is a blood sample that is spun in a centrifuge, separating the plasma. The coagulation cascade is triggered by calcium and activating substances. The PTT is the time it takes for a blood clot to form.


Which drug effect does the partial thromboplastin time test monitor?

The PTT test can be used to monitor the effect of heparin on a patient's coagulation system.


What is a Partial thromboplastin time?

A test to check your blood clotting.


How is the partial thromboplastin time test usually paid for?

The partial thrmoboplastin time test is usually covered by insurance.


What are the risks associated with a partial thromboplastin time test?

Complications of a bruise or swelling around the puncture site, which can be treated with moist warm compresses. People with coagulation problems may bleed for a longer period than normal.


What does the medical abbreviation APTT mean?

APTT stands for Activated Partial Thromboplastin Time. It's a medical test that, in simple terms, is used to see how long it takes your blood to clot. This can be useful in diagnosing disorders such as Von Willebrand in which the blood has trouble clotting. The test can also be used to see how effectively blood thinning agents such as Heparin are working.


Medical term p.t.t. head?

PTT = Partial Thromboplastin Time (test). Don't know what and how 'head' relates to this.


What are the precautions associated with the partial thromboplastin time test?

Precautions are that certain medications (antihistamines, vitamin C, aspirin and chlorpromazine) can affect the results of the PPT test.


What does activated PTT mean in a coagulation study?

The activated partial thromboplastin time (APTT) test is used after you take blood-thinners to see if the right dose of medicine is being used. If the test is done for this purpose, an APTT may be done every few hours. When the correct dose of medicine is found, you will not need so many tests.


What is the use of adding activators to a partial thromboplastin time test?

The test can be done without activators, but they are usually added to shorten the clotting time, making the test more useful for monitoring heparin levels.


What does a coag panel include?

A "coag panel", or coagulation panel is a blood test to look at the ability of your blood to clot. One sample of blood is taken, usually in a special "vacutube" and is combined with citrate to prevent clotting in the tube. A series of tests is then performed on it in a lab. A coag panel usually comprises an activated partial thromboplastin time (APTT), prothrombin time (PT), and platelet count. An International normalised ratio (INR) can be calculated from the PT. Each test measures the effectiveness of different parts of the clotting cascade (a series of reactions that occur when blood clots.)


What are normal results for a partial thromboplastin time test?

Partial thromboplastin time test results can be obtained in less than one hour.