So, you want that kind of mainstream anime?
Well, here's a list of the ones that I thought were good. Some may not be too mainstream, but are still just as good.
Gintama
Code Geass
Full Metal Alchemist
Full Metal Panic
D.Grayman
Gundam 00
Gurren Laggan
Busou Renkin
Darker than Black
Nurarihyon no Mago
Sengoku BASARA
Rosario to Vampire
Soul Eater
Shakugan no Shana
Toaru Majutsu no Index
Utawarerumono
Try One Piece.
Bleach and Naruto
Bleach One Piece Naruto
Naruto or Bleach. either of the two. :))
The most popular Anime as of now has to be either Naruto or Bleach.
Full metal alchemist Bleach Naruto
Crunchyroll.com
Bleach, Naruto, Naruto Shippuden, Devil May Cry, Hellsing, (one anime) Katekyo Hitman Reborn, and Inuyasha. I know you will enjoy these anime.
Orihime-Bleach Ochimaru(Orchimaru?)-Naruto
Bleach.
naruto->one piece->bleach http://www.animecrazy.net/most-popular/
I would recommend Ouran High School Host Club, Bleach, and Naruto/Naruto Shippuden.