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The term itself refers to the gradual shift of something over time.

More specifically, in Biology it refers to the gradual shift in traits in a population as caused by natural selection. Traits which are harmful or cause an organism to have a decreased chance to survive are 'selected against' in that they are less likely to pass on those traits. Likewise, traits which are beneficial cause there to be an increased chance the organism will survive to pass on it's traits.

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