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What is affected in ALS?

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Anonymous

8y ago
Updated: 2/12/2022

Chromosome 21q22 which accounts for 20% of familial ALS.

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Zoie Bergstrom

Lvl 13
3y ago

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What organ systems that are affected by ALS?

ALS is a disease of the neuromuscular system.


In als what chromosome is affected?

In ALS, also known as amyotrophic lateral sclerosis, the chromosome primarily affected is chromosome 9. A gene called C9orf72 located on this chromosome is linked to a significant percentage of familial ALS cases. Other genetic mutations on different chromosomes can also contribute to ALS development.


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Some of the symptoms of ALS include twitching, muscle weakness in the hands, arms, and legs may occur also. Ones speech can be affected and alter slightly at the onset of ALS.


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ALS progresses rapidly in most cases. It is fatal within three years for 50% of all people affected, and within five years for 80%. Ten percent of people with ALS live beyond eight years.


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What are the symptoms of ALS disease?

Common symptoms of ALS include weakening of the muscles, twitching and cramping in the muscles, impairment of the use of the arms and legs, difficulty in projecting the voice and shortness of breath and difficulty breathing and swallowing. ALS is often treated through a series of medications, but none are proven to slow the progression of the disease.


How many people die from als each year?

Around 5,000-6,000 people die from ALS each year in the United States. It is a progressive neurodegenerative disease with no cure that primarily affects the nerve cells responsible for controlling voluntary muscles. Early diagnosis and multidisciplinary care are important in managing symptoms and improving quality of life for those affected by ALS.


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Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS), is primarily caused by mutations in the C9orf72, SOD1, FUS, and TARDBP genes. These mutations can lead to the degeneration of motor neurons in the brain and spinal cord. ALS is not specifically linked to a particular chromosome.


When was Hilton Als born?

Hilton Als was born in 1961.


When did Peder Als die?

Peder Als died in 1775.


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Peder Als was born in 1725.