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Littlest is a synonym for smallest. It begins with the letter L.
least
Qua is a word. It begins with the letter Q.
littlest
a or I The letter "a" as in... The man has ahat.
molecule
cell
The one-letter words I and a are pretty short.
DNA
Yes, 'worlds' is a real word.
the smallest living part of organism The actually meaning is that of a small room that monks lived in.
The smallest compound word may be into.