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What is an LDA reaction in science?

Updated: 9/23/2023
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LDA stands for lithium diisopropylamide. This compound causes a number of reactions, including the alkylation and halogenation of enolates, and the Aldol reaction.

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Q: What is an LDA reaction in science?
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Is LDA a base?

LDA is a base, and a strong one at that with a pKa of approximately 25 It is typically used for removing hydrogen atoms for aldol reactions since this makes the reaction irreversible and prevents various side reactions occuring. LDA has 2 isopropyl groups attached to a central nitrogen atom which yields a negative charge making the compound basic.


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