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What is the disease called when you do not have sweat glands?
Anhidrotic Ectodermal Dysplasia is a genetic disorder characterized by dysfunctional or absent sweat glands.
What do AED mean?
Anhidrotic ectodermal dysplasia is one of about 150 types of ectodermal dysplasia in humans. Before birth, these disorders result in the abnormal development of structures including the skin, hair, nails, teeth, and sweat glands
How rare is it of people born without sweat glands?
It is extremely rare for people to be born without sweat glands, a condition known as anhidrotic ectodermal dysplasia. This can lead to issues with regulating body temperature and can require special care to prevent overheating. Treatment may involve managing symptoms and using methods to stay cool.
Importance of ninhydrin test in clinical or research laboratory?
Approximately 5% of patients with cervical dystonia receiving repeated botulinum neurotoxin A (BoNT/A) injections develop secondary loss of treatment benefit. Currently available tests to directly detect neutralizing BoNT/A antibodies (BoNT/A-AB) are either expensive or time consuming. To establish a simple, clinically useful test for antibody detection, we adapted the ninhydrin sweat test (NST). Eighteen dystonic patients with secondary nonresponse and clinically suspected BoNT/A-AB formation were tested for BoNT/A-AB in the mouse diaphragm test (MDT). In addition, the size of the anhidrotic area was determined by the NST 21 days after an intradermal dose of 10 U Dysport into the hypothenar region of the left palm. In nine patients, positive BoNT-AB titers were found in the MDT. There was a significant correlation between the BoNT/A-AB titers and the anhidrotic area (Spearman's rho = -0.9, P < 0.0001). Both tests provided comparably good results with respect to qualitative antibody detection. In the clinical situation of secondary nonresponse to BoNT/A therapy, the economical NST may be a helpful tool to detect neutralizing BoNT/A-AB.© 2004 Movement Disorder Societyhttp://www3.interscience.wiley.com/journal/107632044/abstract?CRETRY=1&SRETRY=0© 2004 Movement Disorder Society
Why doctors ask diabetic patients if they have a eye and foot exam?
For starters, diabetics often have poor blood circulation which in turn causes numerous other problems. As a former nurses assistant I often witnessed residents with diabetes loose feeling/sensation especially in their lower legs and feet. As I understand it, poor blood circulation puts you at risk for a number of blood borne illnesses. Illnesses that in some cases lead to kidney disease/ failure and or limb amputation due to toxins in your blood that can cause infections/diseases like gangrene To the best of my knowledge Dr's monitor your feet in part to determine if your blood is circulating properly. Swelling, numbness, or loss of sensation in your feet could an early warning sign that your diabetes is progressing. I also know that diabetes can lead to poor vision and in some cases blindness.
What foot problems are associated with diabetes?
I'm sure there's a lot of technical descriptions of the actual breakdown at work but the short answer is you have nerve damage and the nerves no longer function properly. People get stabbing pain, throbbing, pressure, feeling like an itch inside the foot that can't be relieved, burning and more. The higher the blood sugar goes, the more the pain.
