An azaindole is any of a group of bicyclic heterocycles composed of a pyridine ring fused with a pyrrole ring.
To prepare 5-cyano-7-azaindole, cuprous cyanide and 5-bromo-7-azaindole are used as the raw materials and can react in an organic solvent at high temperature (100-250 ℃) to generate 5-cyano-7-azaindole, and the 5-cyano-7-azaindole product with high purity can be obtained through simple post-treatment of the system after reaction.
The upstream raw materials of 5-Bromo-7-azaindole include acetic acid, bromine, manganese acetate, zinc powder, boron trifluoride, tert-butyl alcohol, 7-azaindole, and more.