The term refers to cells that line hollow organs & glands & those that make up the outer surface of the body.
Irregular round shape
Although they have no true tissues or organs, they are lined inside and out with flattened cells called epithlium. they r made up of more than one cell
It is the outer layer of skin... roughly thirty layers deep. Its high keratin concentrations keep our body safe, water in, and is a shield. That's it. A shield. It also has melanocytes which alter our pigment.
MetaplasiaMetaplasia (change in form, Greek) is the replacement of one differentiated cell type with another mature differentiated cell type. The change from one type of cell to another is generally caused by some sort of abnormal stimulus. In simplistic terms, it is as if the original cells are not robust enough to withstand the new environment, and so they change into another type more suited to the new environment. If the stimulus that caused metaplasia is removed or ceases, tissues return to their normal pattern of differentiation. CausesThere are three main theories as to how metaplasia occurs:Differentiated cells may change their pattern of differentiation in a process termed transdifferentiation.Local stem cells, which are believed to generate new cells in most tissues, become reprogrammed by the changed environment to form a new form of cell.Circulating stem cells in the blood, which are recognised to colonise tissues, may start to grow in damaged tissues and produce a new form of cell.TreatmentThe medical significance of metaplasia is that in some sites cells may progress from metaplasia, to develop dysplasia, and then neoplasia (cancer). Thus, at sites where metaplasia is detected, efforts are made to remove the causative irritant, thereby decreasing the risk of progression to malignancy. The metaplastic area must be carefully monitored to ensure that dysplastic change does not begin to occur. A progression to significant dysplasia indicates that the area could need removal to prevent the development of cancer.