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What is chemonucleolysis?

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GaleEncyofMedicine

Lvl 1
14y ago
Updated: 8/19/2019

a medical procedure that involves the dissolving of the gelatinous cushioning material in an intervertebral disk by the injection of an enzyme such as chymopapain.

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14y ago

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What type of disk injuries is chemonucleolysis used with?

Chemonucleolysis is effective on protruded and extruded disks, but not on sequestered disk injuries.


How does chemonucleolysis work?

Chemonucleolysis uses chymopapain, an enzyme derived from papyrus, to dissolve the disk material that has been displaced because of injury.


When is chemonucleolysis not a treatment option?

Chemonucleolysis should not be performed on patients allergic to chymopapain or papaya. It also should not be done: when the patient is pregnant, if the disk is sequestered, if the patient has had several failed back operations.


What risks are associated with chemonucleolysis?

The greatest risk is that the patient may be allergic to chymopapain. The death rate for chemonucleolysis is only 0.02%. Complications overall are five to 10 times less than with conventional surgery.


How long does it take for chemonucleolysis to work?

Many patients feel immediate relief from pain, but, in about 30% of patients, maximal relief takes six weeks


What happens during a chemonucleolysis treatment?

A small gauge needle is placed in the center of the affected disk. Chymopapain is introduced into the disk. The patient needs to remain still.


What types of activities are restricted after a chemonucleolysis?

Patients may feel lower back stiffness, which goes away in few weeks. Heavy lifting and sports activities should be avoided for at least three months.


What has the author John A McCulloch written?

John A. McCulloch has written: 'The Dilemma of Modernity' 'Sciatica and chymopapain' -- subject(s): Chemonucleolysis, Chemotherapy, Chymopapain, Hernia, Injections, Intradiscal, Intervertebral disk, Intradiscal Injections, Sciatica, Therapeutic use


Different Options For Bulging Disc Treatment?

A bulging disc is a condition that occurs along the spine of an individual. The disc is a padded area that acts as a cushion between the vertebrae of the spine. The interior of the disc is made from a thick fluid called nucleus polposus, and the surrounding harder cartridge that contains the fluid is known as the annulus fibrosis. The bulge occurs when the fluid presses on the outer shell of the disc, forcing it to expand outwards beyond the area of the spine. A spinal bulging disc is different than a herniated disc in that the surface of the annulus fibrosis is not damaged, but is merely deformed by pressure. Many people experience a bulging disc at some point. The condition can become more common with age or overexertion. In reality, a healthy person without other existing medical conditions that could affect the spine or healing time can expect to see a properly rested bulging disc heal itself within one to two months. In cases where the bulge is causing only minor pain and is likely a result of overextension, overexertion, or poor posture, rest and some stretching is the most commonly suggested bulging disc treatment. In some situations, bulging disc can become a chronic condition. Physical therapy that relieves pressure on the disc, and education about the correct way to move the spine, can help to give the disc time to heal itself over time. For more stubborn situations, a posterior brace or traction might be used to relieve pressure and to prevent the spine from moving into a potentially damaging position. Occasionally, this type of bulging disc treatment is accompanied by pain relievers or muscle relaxers. When other options such as cortisone injections, traction, braces, and exercise have been exhausted, or when the pain is preventing normal daily activities, then there are some surgical bulging disc treatment options. A procedure known as chemonucleolysis can be used to introduce a chemical into the nucleus polposus so that it will reduce in size. A hemilaminectomy might be performed when other options have failed, removing part of the actual vertebrae with the intention of relieving pressure on the disc so it will not bulge. Finally, a discectomy can be performed in order to remove the disc itself, although this can eventually lead to other types of back pain and could potentially require follow-up surgery.