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What is corneaplasty?

Updated: 4/28/2022
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Corneaplastytm, is a non-surgical procedure that changes the shape of the cornea (the front part of the eye) using modern Ortho-K contact lenses as corneal molds, in conjunction with certain medications to prepare and final-set the cornea. This is a mechanico-chemical procedure.

Corneaplastytm is essentially a 3-step process. First, the cornea is "prepared" by applying a proprietary (ACS-005 enz) concentration of the human enzyme, hyaluronidase, which absorbs into the cornea, making it softer and more "malleable" for a period of time, says Hampar Karageozian, senior vice president of research and development at Advanced Corneal Systems. The drug temporarily alters the molecular bonds between proteoglycan molecules in the cornea. This enzyme has a long history of safe use in ophthalmic (eye-related) and other applications. Second, the "prepared" cornea is then molded to the desired shape with custom fitted AOK contact lenses worn during the treatment period. Thirdly, a proprietary cross-linking agent "fixative" drop is administered to "set" the cornea in its optimum shape. It effectively "glues" the collagen fibrils until they re-grout naturally. Moreover, the procedure is reversible, i.e. it can return the cornea to its pre-altered state if desired; and, it (the cornea) is alterable indefinitely throughout life, so the procedure is repeatable. You can "fix," "reverse" or "alter." There is no ablation or cutting of tissue. There is only a bending of the cornea and a migration of corneal epithelium.

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Who is the most famous welsh inventor?

Edward George Bowen pioneer of radar. Worked at 'Woomera Rocket Testing Base' in Australia. Born in Gendros, Swansea.David Brunt pioneer of modern meteorology. Head of Meteorological Office, secretary of Royal Society From Penfforddlas, Wales.Martha Hughes Cannon pioneer in women and children's medicine. The State of Utah's Health Department is named in her honour. Born in Llandudno, Wales.Archie Cochrane Founder of Cochrane Collaboration, Cochrane library, Cochrane reviews. UK Cochrane Centre in Oxford. Conducted much of his groundbreaking medical research in WalesAlan Cox is a programmer heavily involved in the development of the Linux kernel since 1991.Sir Clifford Darby, geographer and leader in promoting the relationships between geography and other subjects. Knighted in 1988. Born in Neath, South WalesDonald Davies Proposed and developed packet switching an important part of the internet. Born in Treorchy, Rhondda, WalesWalter Davies (inventor), along with his brother Thomas, invented the 'Stepney Spare Wheel' used on almost all early motor cars. Born in Llanelli, South WalesJohn Dee Founder of the new school of English mathematical scientists in 16th century. One of the greatest polymaths of all time. Born in Buallt, Radnor.Bill Frost Welsh carpenter who patented the aeroplane in 1894 and took to the skies in a powered flying machine the following year, eight years before the Wright brothers attempt at Kitty Hawk. Born in TenbyWilliam Robert Grove Invented the Fuel Cell. Born in Swansea, 1811John T. Houghton Distinguished meteorologist. Inspiration behind major international conferences on global warming (Rio, Kyoto, Buenos Aires). Born in Wales.]David E. Hughes First transmission of radio waves. Inventor of the microphone and printing telegraph system. A musician and philosopher. Born Corwen, Wales.John Gwyn Jeffreys conchologist (someone who studies shells). He helped pioneer deep-sea dredging. He corresponded with Charles Darwin and was involved with a number of scientific associations. Born into a long-established Welsh family.Ernest Jones He introduced psychoanalysis into Britain and North America. Born in Llwchwy, South WalesSamuel Milton Jones Inventor, writer and Mayor of Toledo, Ohio, USA. Born in CarnarvonshireSteve Jones Professor of genetics at the Galton Laboratory and University College, London. Born in Wales.William Jones A noted mathematician, published author and early naval navigator. First to use 'Pi' (1706) as a mathematical symbol. Born in Llanfihangel Tre'r Beirdd.Brian Josephson Nobel prize winning physicist; gave his name to 'Josephson Effects'. Born Cardiff.Bernard Knight Forensic pathologist, barrister and writer. Creator of the 'Crowner John' series, historic crime fiction. As a forensic pathologist, worked on the infamous Fred West case, recovering all twelve bodies. Born and spent most of his life in Cardiff.Francis Lewis Signatory of the US 'Declaration of Independence' as one of the representatives from New York. Born in LlandaffEdward Lhuyd Fellow of Jesus College Oxford. Keeper of the Ashmolean Museum and the foremost Celtic scholar of his time. Born Oswestry, 1660Ronald M Lockley Famous naturalist and author. Best known for his life on Skokholm Island off Pembrokeshire 1927-1940 and at Orielton in 1950's early 1960s. Born in Cardiff.Terry Matthews 'Mitel' and 'Newbridge' Networks founder. Born and raised in Wales.William Morgan Inventor of the Vacuum Tube, Coolidge Tube, Britain's first actuary, founding father of modern actuarial science. The unknowing discoverer of x-rays, a hundred and ten years before Roentgen. Born in Bridgend, 1750, died 1830.William Henry Preece was an electrical engineer who was a major figure in the development and introduction of wireless telegraphy and the telephone in Great Britain. Born Feb 15 1834 in Bryn Helen.[Richard Price Was developer of the times tables for insurance scales. Born at Tynton Farm Llangeinor, South WalesWilliam Price re-introduced cremation to Britain. Born Llantrisant, South WalesPryce Pryce-Jones Gave mail-order (catalogue) shopping to the world.(circa 1859) Born/lived in Newtown, Montgomeryshire (Powys).Robert Recorde Very influential physician and mathematician. Robert published some of the most important books of his era including the first English language book on Algebra which incidentally is where the equals symbol is first seen in use. From Tenby, West WalesIsaac Roberts He pioneered deep space photography at the end of the 19th century. Born in Groes near Denbigh in 1829.Richard Roberts (engineer) Textile machinery, railway locomotives and other industrial inventions. Born Llanymynech, 1789.Bertrand Russell Philosopher, mathematician and the Nobel Prize for Literature in 1950. Russell is one of the most highly regarded academics of the 20th century. He popularized mathematics and proposed many ground breaking theories. Born in Trelleck, Monmouthshire, South Wales.David Thomas in 1837 invented a hot blast furnace process to make iron using anthracite coal in Ystradfera (Swansea Valley). transforming the iron-making process there and later in 1839 after re-locating to Pennsylvania where he became the "father" of the American steel industry with his inventionSir Tudor Thomas World famous Welsh eye surgeon from Cardiff. He pioneered ophthalmic corneaplasty in the 1930s. Born in Ystradgynlais 23 May 1893Alfred Russel Wallace Conferred with Darwin (and Darwin with him) regarding evolution of species and acknowledged as theory co -founder by Darwin in his 'On the Origin of Species'. Born South Wales.Evan Williams Distinguished physicist, discoverer of the Meson Particle. Born Cwmsychpant, Llandysul, Wales.Ernest Willows pioneering aviator. 'The Father of British Airships' Born in Cardiff, 1896.


What is the most popular thing that the welsh invented?

Theres a huge range of Welsh Based invetions and discoveries to choose from such asDavid Thomas in 1837 invented a hot blast furnace process to make iron using anthracite coal in Ystradfera (Swansea Valley). transforming the iron-making process there and later in 1839 after re-locating to Pennsylvania where he became the "father" of the American steel industry with his inventionEddie Bowen pioneer of radar. Worked at 'Woomera Rocket Testing Base' in Australia. Invented artificial rain in the 1950s Born in Gendros, Swansea.David Brunt pioneer of modern meteorology. Head of Meteorological Office, secretary of Royal Society From Penfforddlas, Wales.Martha Hughes Cannon pioneer in women and children's medicine. The State of Utah's Health Department is named in her honour.Born in Wales. Family from Llanddoged near Llanrst.John Chiplin Co-founder of 'GeneFormatics', leading biotech company, in 1999. Founded 'Newstar Music' 1995 and creative vehicle for the band, 'Vita Nuova'. Born in Cardiff.Archie Cochrane Founder of Cochrane Collaboration, Cochrane library, Cochrane reviews. UK Cochrane Centre in Oxford. Conducted much of his groundbreaking medical research in Wales. Cochrane archive is in Llandough Hospital, part of Cardiff University School of Medicine.Iian Cox Alan cox is a programmer heavily involved in the development of the Linux kernel since its early days (1991). He then became one of the main developers and maintainers of the whole kernel.Sir Clifford Darby Geographer and leader in promoting the relationships between geography and other subjects. Knighted in 1988. Born in Neath, South Wales.Donald Davies Proposed and developed packet switching an important part of the internet. Born in WalesThomas Davies Along with his brother Walter he invented the 'Stepney Spare Wheel' used on almost all early motor cars. Born in Llanelli, South WalesJohn Ddu Founder of the new school of English mathematical scientists in 1500's. One of the greatest polymaths of all time. Born in Buallt, Radnor.Mr Dudson Invented the DUDSON Valve (the needle type) used to inflate sports balls everywhere. Lived in Abertridwr.Sir Chris Evans Britain's most colourful biotech entrepreneur. Born in Port Talbot.Bill Frost Welsh carpenter who patented the aeroplane in 1894 and took to the skies in a powered flying machine the following year, eight years before the Wright brothers attempt at Kitty Hawk. Born in Tenby.William Robert Grove Invented the Fuel Cell. Born in Swansea, 1811.John Houghton Distinguished meteorologist. Inspiration behind major international conferences on global warming (Rio, Kyoto, Buenos Aires). Born in Wales.David Hughes First transmission of radio waves. Inventor of the microphone and printing telegraph system. A musician and philosopher. Born Corwen, Wales.John Gwyn Jeffreys conchologist (someone who studies shells). He helped pioneer deep-sea dredging. He corresponded with Charles Darwin and was involved with a number of scientific associations. Born into a long-established Welsh family.Dyfrig Jones Theory of 'Planetary Radiation'. Born in Wales.[citation needed]Ernest Jones He introduced psychoanalysis into Britain and North America. Born in Llwchwy, South WalesSamuel Milton Jones Inventor, writer and Mayor of Toledo, Ohio, USA. Born in Carnarvonshire.Steve Jones Professor of genetics at the Galton Laboratory and University College, London. Born in Wales.William Jones A noted mathematician, published author and early naval navigator. First to use 'Pi' (1706) as a mathematical symbol. Born in Llanfihangel Tre'r Beirdd.Brian Josephson Nobel prize winning physicist; gave his name to 'Josephson Effects'. Born Cardiff.Bernard Knight Forensic pathologist, barrister and writer. Creator of the 'Crowner John' series, historic crime fiction. As a forensic pathologist, worked on the infamous Fred West case, recovering all twelve bodies. Born and spent most of his life in Cardiff.Francis Lewis Signatory of the US 'Declaration of Independence' as one of the representatives from New York. Born in Llandaff.Edward Lloyd Fellow of Jesus College Oxford. Keeper of the Ashmolean Museum and the foremost Celtic scholar of his time. Born Oswestry, 1660.Ronald M Lockley Famous naturalist and author. Best known for his life on Skokholm Island off Pembrokeshire 1927-1940 and at Orielton in 1950's early 1960s. Born in Cardiff.John Maddox Knighted for services to science. Author of several books. Born South Wales, 1925.Terence Matthews 'Mitel' and 'Newbridge' Networks founder. Billionaire. Born and raised in Wales.Gaynor Morgan Inventing and patenting the 'inco-stop'. Born in Bridgend.Kevin Morgan Groundbreaking work in the field of Pharmaceutical powder compacting. Born in Swansea.William Morgan (scientist) Inventor of the Vacuum Tube, Coolidge Tube, Britain's first actuary, founding father of modern actuarial science. The unknowingly discoverer of x-rays, a hundred and ten years before Roentgen! Born in Bridgend, 1750, died 1830Sir William H Preece William Henry Preece was an electrical engineer who was a major figure in the development and introduction of wireless telegraphy and the telephone in Great Britain. Born Feb 15 1834 in Bryn Helen.Dr Richard Pryce Was developer of the times tables for insurance scales. Born at Tynton Farm Llangeinor, South WalesDr William Price re-introuduced cremation to Britain. Born Llantristant, South WalesPryce Pryce-Jones Gave mail-order (catalogue) shopping to the world.(circa 1859) Born/lived in Newtown, Montgomeryshire (Powys).Robert Recorde Very influential physician and mathematician. Robert published some of the most important books of his era including the first English language book on Algebra which incidentally is where the equals symbol is first seen in use! He achieved high office too, being not only the king's physician but also the controller of the Royal Mint (which is now based in Llantrisant, South Wales). From Tenby, West Wales.Isaac Roberts He pioneered deep space photography at the end of the nineteenth century. Born in Groes near Denbigh in 1829.Richard Roberts Textile machinery, railway locomotives and other industrial inventions. Born Llanymynech, 1789.Earl Bertrand Russell Philosopher, mathematician and the Nobel Prize for Literature in 1950. Russell is one of the most highly regarded academics of the twentieth century. Helped perhaps by a great sense of humor, he popularized the mathematics and proposed many ground breaking theories. Born in Trelleck, Monmouthshire, South Wales.f Sir John M. Thomas Former Director of the Royal Institution. Previously held Chair of Physical Sciences at Cambridge. Before that Professor and Head of Chemistry Department at Aberystwyth. Member of the Bardic Circle of the National Eisteddfod.Born in Wales of Welsh parentage.Sir Tudor Thomas World famous Welsh eye surgeon from Cardiff. He pioneered ophthalmic corneaplasty in the 1930s. Born in Ystradgynlais twenty-third May 1893.Brian Trubshaw Test Pilot for Concorde. From Llanelli, Wales.Alfred Russel Wallace Conferred with Darwin (and Darwin with him) regarding evolution of species and acknowledged as theory co -founder by Darwin in his 'On the Origin of Species'. Born South Wales.Evan Williams Distinguished physicist, discoverer of the Meson Particle. Born Cwmsychpant, Llandysul, Wales.Ernest Willows pioneering aviator. In 1910 became the first person to cross the English channel in airship. Born in Cardiff, 1896.With thansk to my colleagues in Wikipedia for their help


Who is the most famous Welsh scienceist?

Here is a list of some welsh scientists Alfred WallaceConferred with Darwin (and Darwin with him) regarding evolution of species and acknowledged as theory co -founder by Darwin in his 'On the Origin of Species'.Ronald LockleyFamous naturalist and author. Best known for his life on Skokholm Island off Pembrokeshire 1927-1940 and at Orielton in 1950's early 1960's.Herbert StuartDeveloped and patented a compression ignition engine by 1885. Diesel only had his version working twelve years later in 1897.Donald DaviesProposed and developed packet switching an important part of the internet.Bill FrostWelsh carpenter who patented the aeroplane in 1894 and took to the skies in a powered flying machine the following year, eight years before the Wright brothers attempt at Kitty Hawk.Harry Grindell-MatthewsWacky inventor of so called 'Death Ray' and various electrical devices including burglar alarms, projectors and automatic street lighting.Sir Tudor ThomasWorld famous Welsh eye surgeon from Cardiff. He Pioneered ophthalmic corneaplasty in the 1930's.Pryce Pryce-JonesGave mail-order (catalogue) shopping to the world.(circa 1859)William GroveInvented the Fuel Cell.DudsonInvented the DUDSON Valve (the needle type) used to inflate sports balls everywhere.Robert RecordeVery influential physician and mathematician. Robert published some of the most important books of his era including the first English language book on Algebra which incidentally is where the equals symbol is first seen in use! He achieved high office too, being not only the king's physician but also the controller of the Royal Mint (which is now based in Pontyclun, South Wales).As is true today, positions of power attract enemies and sadly it was his high profile that lead to his downfall. Robert was broken by a law suit and as a bankrupt was sent to debtours jail at Southwark where he died.Dr Richard PryceWas developer of the times tables as a teaching aid and re-introduced cremation to Britain.Francis LewisSignatory of the US 'Declaration of Independence' as one of the representatives from New York.Eddie BowenPioneer of Radar. Worked at 'Woomera Rocket Testing Base' in Australia. Invented artificial rain in the 1950's.Terence Matthews'Mitel' and 'Newbridge' Networks founder. Billionaire.  Edward LloydFellow of Jesus College Oxford. Keeper of the Ashmolean Museum and the foremost Celtic scholar of his time.Samuel JonesInventor, writer and Mayor of Toledo, Ohio, USA.Ernest JonesHe introduced psychoanalysis into Britain and North America.Sir Clifford DarbyGeographer and leader in promoting the relationships between geography and other subjects. Knighted in 1988.Earl Bertrand RussellPhilosopher, mathematician and the Nobel Prize for Literature in 1950. Russell is one of the most highly regarded academics of the 20th century. Helped perhaps by a great sense of humour, he popularized the mathematics and proposed many ground breaking theories. As significant as they are, his theories were not entirely responsible for his reputation. He felt free to comment at an international level on matters as diverse as the Cold War, Kennedy's assassination and the Vietnam War. So much so, that at the height of his reputation many of his devout followers regarded him as a guru.Martha CannonA pioneer in Women and Children's medicine. The State of Utah's Health Department is named in her honour.Brian TrubshawTest Pilot for Concorde.William JonesA noted mathematician, published author and early naval navigator. First to use 'Pi' (1706) as a mathematical symbol. He was a friend of Isaac Newton and Edmund Halley. Father of William Jones the philologist who identified the Indo-European language group which connects many early languages (Sanskrit, Greek, Latin - even Welsh) together.David HughesFirst transmission of radio waves. Inventor of the microphone and printing telegraph system. A musician and philosopher.Brian JosephsonNobel prize winning physicist; gave his name to 'Josephson Effects'.Evan WilliamsDistinguished physicist, discoverer of the Meson Particle.John HoughtonDistinguished meteorologist. Inspiration behind major international conferences on global warming (Rio, Kyoto, Buenos Aires).Dyfrig JonesTheory of 'Planetary Radiation'.Thomas MorganNobel prize for medicine 1933. A pioneer in genetics.Wendell StanleyNobel prize for Chemistry.David BruntPioneer of modern meteorology; head of Meteorological Office, secretary of Royal Society.Isaac RobertsHe pioneered deep space photography at the end of the nineteenth century.Frank Hope-JonesDeveloped the 'Synchronize' electric clock system. He devised the 'pip' time signal first broadcast by the BBC and later by most of the world's major broadcasting organisations.John ChiplinFounded 'Geneformatics', leading biotech company in 1999. Founded 'Newstar Music' 1995 and creative vehicle for the band, 'Vita Nuova'.Sir John Thomas (Prof)Former Director of the Royal Institution. Previously held Chair of Physical Sciences at Cambridge. Before that Professor and Head of Chemistry Department at Aberystwyth. Member of the Bardic Circle of the National Eisteddfod.  YaleThe Inventors of Yale Locks.Kevin MorganGroundbreaking work in the field of Pharmaceutical powder compacting.Edward RobertsBiochemistrySir Chris EvansBritain's most colourful biotech entrepreneur, 'The Welsh wizard'.Laurence MatthewsHe was a scientist who helped clone the first sheep who became known as Dolly.Gaynor MorganInventing and patenting the 'inco-stop'.John MaddoxKnighted for services to science. Author of several books.Alan BeckwithFilms include 'The China Syndrome' in 1979. TV series including 'The Lindbergh Kidnapping Case' and 'From here to Eternity'.John DduThe outstanding British scientist of his time. Founder of the new school of English mathematical scientists in 1500's. One of the greatest polymaths of all time.Bernard KnightForensic pathologist, barrister and writer. Creator of the 'Crowner John' series, historic crime fiction. As a forensic pathologist, worked on the infamous Fred West case, recovering all twelve bodies!Ernest WillowsPioneering aviator. In 1910 became the first person to cross the English channel in airship.Richard RobertsTextile machinery, railway locomotives and other industrial inventions.Thomas DaviesAlong with his brother Walter he invented the 'Stepney Spare Wheel' used on almost all early motor cars.William MorganInventor of the Vacuum Tube, Coolidge Tube, Britain's first actuary, founding father of modern actuarial science, and wait for it! The discoverer of x-rays, a hundred and ten years before Roentgen!John JeffreysHe was one of the greatest conchologists (someone who studies shells) of the 19th century. His main set of five books is much sought after as a collector's item. His collection became the world's greatest for the time. He helped pioneer deep-sea dredging. He corresponded with men like Charles Darwin and was involved with a number of scientific associations Willam JonesA brilliant linguist William studied and eventually related the Indo European language family which connects Greek, Latin and even Welsh! He also met with Ben Franklin to discuss a peaceful settlement in the American War of Independence.Alan CoxAlan Cox (born 1968) is a programmer heavily involved in the development of the linux kernel since its early days (1991). He then became one of the main developers and maintainers of the whole kernel. This is an extremely important contribution to the 'Open Source' software community.Sir William PreeceWilliam Henry Preece was an electrical engineer who was a major figure in the development and introduction of wireless telegraphy and the telephone in Great Britain.Steve JonesProfessor of genetics at the Galton Laboratory and University College, London.John LloydAccording to 'Kremers and Urdang's History of Pharmacy' was 'one of the greatest pharmacists and chemists America has ever had'. Won three Ebert Prizes and Remington Medal. Served as president of American Pharmaceutical Association 1887 to 1888. Numerous inventions.Archie CochraneFounder of Cochrane Collaboration, Cochrane library, Cochrane reviews. UK Cochrane Centre in Oxford.Jerry DaviesJerry founded Davies Veterinary Specialists, one of the most successful veterinary referral hospitals in Europe.Sir Clement ThomasSurgeon to the late kingMichael MoritzMichael is a venture capitalist with sequoia capital in California. And a former member of the board of google inc. His Internet investments include google, youtube, etoys, eBay, yahoo! , paypal and Apple computers. His investment in google has made him one of Wales' richest men.John GuestJohn guest was the only surviving son of Thomas Guest an iron-master, he took over his fathers company in Merthyr in 1807. Guest was a shrewd businessman by the 1830's the Dowlais ironworks was the largest in the world.John DaviesHe was an athlete and winner of a Gold Medal in 4x400m relay at the Antwerp summer Olympics in 1920.Inigo JonesA meteorologist and farmer. In 1874 Jone's parents migrated to Australia, settling on a property called Crohamhurst in the glass house mountains north of Brisbane in eastern Queensland. He became interested in meteorology while working on the family farm.Neil WalkerFor his work in the creation and development of the Intel corporation responsible for the Intel processors.Jane MatthewsInvention of a new product, PlugPal and development through to marketing of product and sales. It gained a Bronze Medal at the Prestigious International Exhibition of Inventions.Dr Lyn EvansDr Lyn Evans CBE is leader of the large hadron collider project. Dr Evans gained his PHD from the University of Swansea in 1970 and became a research fellow at CERN in the same year. He is a fellow of the American Physical Society, a fellow of the University of Wales.Dr Evan PierceFought cholera epidemic in Denbigh. Advisor to Queen Victoria. Coroner for Denbighshire. Alderman, JP and Mayor of Denbigh five times.Started local fire brigade. There was a large statue of him erected during his life in Denbigh. Died 1895. Whole town turned out to see his funeral.