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Q: What is cushing syndrome is the result of high production levels?
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What is the medical term meaning the result of prolonged exposure to high levels of cortisol?

Cushing's Syndrome


What is the concept of cushing about?

"Cushing" refers to Cushing's syndrome, an issue that results from high exposures to the hormone cortisol. The syndrome will result in a tumor appearing on the pituitary gland.


Can a benign adrenal tumor cause weight gain?

Yes, it can. Search online for information related to Cushing's Diease (pituitary-originated), and Cushing's Syndrome (adrenal-originated). Cushing's is an over-production of Cortisol, which can result in many, different, seemingly unrelated symptoms. If you believe you have Cushing's see your primary care physician or an endocrinologist for help.


What occurs when large doses of glucocorticoids are given over a period of time?

High levels of circulating cortisol, due to administration of doses of glucocorticoids over a span of time, can result in a condition known as Cushing's syndrome.


What occurs when large dose of glucocorticoids are given over a period of time?

High levels of circulating cortisol, due to administration of doses of glucocorticoids over a span of time, can result in a condition known as Cushing's syndrome.


What causes Pathologic?

Pathological hypercortisolemia, or Cushing's syndrome, named after the United States surgeon, Harvey Cushing (1869-1939), may result from a lung cancer , tumor of the pituitary or adrenal glands, or from kidney failure.


What causes pathological hypercortisolemia?

Pathological hypercortisolemia, or Cushing's syndrome, named after the United States surgeon, Harvey Cushing (1869-1939), may result from a lung cancer , tumor of the pituitary or adrenal glands, or from kidney failure.


What is Cushing's Disease or Cushing's Syndrome?

Patients with Cushing disease have a tumor that secretes a hormone called corticotropin (also called adrenocorticotropic hormone, or ACTH). ACTH is a hormone normally produced by the body (specifically the part of the brain called the pituitary gland) and acts on the adrenal glands, causing them to produce a hormone called cortisol. Cortisol is an important stress hormone that has a number of effects on the body.The ACTH-producing tumor of Cushing disease results in excessively high levels of cortisol in their bloodstream. The cortisol acts throughout the body, causing a redistribution of fat (causing abdominal obesity and two conditions called "moon facies" and "buffalo hump"), thinning of the skin (leading to skin lesions called striae), bone weakness, high blood glucose (which can lead to diabetes), and other conditions.This collection of signs and symptoms is called Cushing syndrome, which is distinct from Cushing disease. Cushing syndrome can be seen in any circumstance where the levels of cortisol are elevated; this frequently happens in patients that are taking cortisol prescribed by their doctor. Cushing disease is excess cortisol caused by an ACTH-secreting tumor.Cushing's disease mainly refers to the manifestation of Cushing's syndrome which is the result of a pituitary gland tumour. The lower portion of the brain has the pituitary gland which controls cortisol production within the body. One of the important causes of this disease could be the small tumours which may cause the adrenal glands to produce too much cortisol resulting in significant changes to the body. In reality, the tumours are not said to be typically malignant or cancerous but if enlarged may lead to vision impairment.


What can cause abnormally low FSH levels?

Anorexia nervosa and disorders of the hypothalamus or pituitary gland can result in abnormally low FSH levels. Abnormal levels can also indicate: infertility hypopituitarism klinefelter syndrome (in men) turner syndrome ovarian failure


If the trend of production of fuel energy falls behind the levels of consumption what could result?

scarcity of energy...


What If the trend of production of fuel energy falls behind the levels of consumption what could result?

The most immediate result would be increased prices, then reduced availability.


Ectopic Cushing syndrome?

DefinitionEctopic Cushing syndrome is a condition in which a tumor outside the pituitary or adrenal glandsproduces a hormone called adrenocorticotropic hormone (ACTH).Alternative NamesCushing syndrome - ectopicCauses, incidence, and risk factorsCushing syndromeis the result of too much glucocorticoid hormones being released over a long period of time. About 15% of Cushing syndrome cases are due to ectopic Cushing syndrome.Ectopic Cushing syndrome is caused by tumors that release adrenocorticotropic hormone (ACTH). Other causes of Cushing syndrome are:Excess release of ACTH by the pituitary glandLong-term use of corticosteroid drugs (commonly used to treat conditions such as rheumatoid arthritis and asthma)Tumor of the adrenal glandTumors that can, in rare cases, release ACTH include:Islet cell tumors of the pancreasMedullary carcinoma of the thyroidSmall cell tumors of the lungTumors of the thymus glandSymptomsEctopic Cushing syndrome tends to have fewer dramatic symptoms than classic Cushing syndrome, but it can occur with higher blood pressure and a lower potassium level. Weight loss may occur due to cancer.Symptoms of Cushing syndrome are:Abdomen sticks out; arms and legs are thin (central obesity)Acne or minor skin infectionsBuffalo humpHeadacheImpotence (in men)Increased urinationMenstrual cycle stops (in women)Mental changesPurple stretch marks on the skin of the abdomen, thighs, and breastsRound, red, and full face (moon face)Tanning or darkening of the skinThirstWeaknessSigns and testsTests that may be done include:24-hour urine for cortisol and creatinineBlood tests to check ACTH, cortisol, and potassium levelsDexamethasone suppression testFasting glucoseMRI and CT scans to find tumorsTreatmentThe best treatment for ectopic Cushing syndrome is surgery to remove the tumor. Surgery is usually possible when the tumor is noncancerous (benign).In some cases, the tumor is cancerous and spreads to other areas of the body before the health care provider can discover the problem with cortisol production. Surgery may not be possible in these cases, but the doctor may prescribe drugs to block cortisol production.Expectations (prognosis)Surgery to remove the tumor may lead to full recovery, but there is a chance that the tumor will come back.ComplicationsThe tumor may spread or return after surgery. High cortisol levels may continue.Calling your health care providerCall your health care provider if you develop symptoms of Cushing syndrome.PreventionPrompt treatment of tumors may reduce the risk in some cases. Many cases are not preventable.ReferencesArnaldi G, Angeli A, Atkinson AB, et al. Diagnosis and complications of Cushing's syndrome: A consensus statement. J Clin Endocrinol Metab. 2003;88:5595-5602.Stewart PM. The adrenal cortex. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR. Williams Textbook of Endocrinology. 11th ed. Philadelphia, PA: Saunders Elsevier; 2007:chap 14.