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Prokaryotes do not have a nucleus included in their cells. Eukaryotes do have a nucleus included in their cells. And prokaryotes are more simple, it is the simplest, but eukaryotes are very complicated. And prokaryotes are single cells, but most of the eukaryotes make a big organism like plants and animals.
Eukaryotes have membranes around their organalles

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Which describes a difference between prokaryotes and eukaryotes?

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