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What are the validation parameters for related substance by hplc analysis?
The validation parameters for related substances analysis by HPLC typically include specificity, linearity, accuracy, precision, detection limit, quantification limit, and robustness. Specificity ensures the method can differentiate between the analyte and impurities, while linearity confirms a linear relationship between concentration and response. Accuracy and precision assess the closeness of results to the true value and the method's repeatability. Detection and quantification limits determine the lowest concentration that can be reliably detected and quantified. Robustness evaluates the method's ability to remain unaffected by small variations in parameters.
What is selectivity factor in chromatography?
The selectivity factor in chromatography is a measure of how well a chromatographic method can separate two components of a mixture. It is calculated as the ratio of the retention factors of the two components. A higher selectivity factor indicates better separation between the two components.
Would a false positive from the reaction between the inoculating loop and hydrogen peroxide be caused by poor specificity or poor sensitivity of the catalase test system?
The false positive from the reaction of hydrogen peroxide and the inoculating loop would be caused by poor specificity. The formula for specificity is TN/TN+FP.
What is the difference between 'collenchyma' and 'chlorenchyma'?
Difference between collenchyma and chlorenchyma
Difference in a charge between two electrodes in a cell causes a ----between electrodes?
Potential difference.
What is the difference between individualization and specificity?
dude, one is a lemon
What the difference between individualization and specificity?
dude, one is a lemon
What is difference between the data validation and data redundancy?
one is a validation the other is redundancy clue is in the name
Difference between verification and validation in software testing?
verification: Are we doing the right system? validation : Are we doing the system right?
What is the difference between SDLC and STLC?
SDLC has both verification and validation activities where as STLC has only validation activity. Simply STLC is a part of SDLC
What is the difference between defect detection and defect prevention?
The defects detection is the validation process. The defects prevention is a verification process.
What is the difference between data varification and data validation?
Data validation makes sure that the data is clean, correct and meaningful, while data verification ensures that all copies of the data are as good as the original.
What are the validation parameters for related substance by hplc analysis?
The validation parameters for related substances analysis by HPLC typically include specificity, linearity, accuracy, precision, detection limit, quantification limit, and robustness. Specificity ensures the method can differentiate between the analyte and impurities, while linearity confirms a linear relationship between concentration and response. Accuracy and precision assess the closeness of results to the true value and the method's repeatability. Detection and quantification limits determine the lowest concentration that can be reliably detected and quantified. Robustness evaluates the method's ability to remain unaffected by small variations in parameters.
What is theDifference between concurrent and prospective validation in pharmaceutical?
If a validation study is conducted before placing a product in the market, then it is called prospective validation. If a product is placed on the market during the validation study, it is called as concurrent validation.
What is selectivity factor in chromatography?
The selectivity factor in chromatography is a measure of how well a chromatographic method can separate two components of a mixture. It is calculated as the ratio of the retention factors of the two components. A higher selectivity factor indicates better separation between the two components.
What is the difference between field level and record level validation rule?
The information entered and how the information is entered is a very dominate role in field/record level validation. However they share the same goal to enforce rules consistently, to write less code.
Explain the relation between sunk costs and specificity?
Specificity refers to the percentage of an investment that will be lost if the asset is switched to another use. Sunk cost is a cost that cannot be avoided once incurred. The relation between them is
