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The exact halfway point is the corner of Ecorse Road and Middlebelt, but that is on a straight line between Wyandotte and Canton.
Firestone Park, OH
Silver Springs, OH is the halfway point.
Johnson city.
Frankfort, IN
Ashland, OH and Wooster, OH
The halfway point between Troy, MI and London KY falls in or around Vandalia, Ohio.
Wooster
Pineton, Pennsylvania is halfway between Ohio and Asbury
The City of Cleveland is most likely the 1/2 way point. Probably somewhere around the end of I-490 and E55th street.
Sugar Grove, Ohio is the halfway point.
Dayton Ohio